Publications

 

2017

Caroça C, Vicente V, Campelo P, Chasqueira M, Caria H, Silva S, Paixão P, Paço J. (2017)
Rubella in Sub-Saharan Africa and sensorineural hearing loss: a case control study.
BMC Public Health. 17(1):146. doi: 10.1186/s12889-017-4077-2.

Caroça C, Vicente V, Campelo P, Chasqueira M, Caria H, Silva S, Paixão P, Paço J. (2017)
DNA repair genes polymorphisms and genetic susceptibility to Philadelphia-negative myeloproliferative neoplasms in a Portuguese population: The role of base excision repair genes polymorphisms.
Oncol Lett. 13(6):4641-4650. doi: 10.3892/ol.2017.6065

Caroça C, Campelo P, Caria H, Paço J, Silva SN. (2017)
G6PD Variants, Malaria and Sensorineural Hearing Loss in São Tomé and Príncipe: A Case-Control Study.
Int J Med Res Health Sci. 6(6): 8-16.

Coady MJ, El Tarazi A, Santer R, Bissonnette P, Sasseville LJ, Calado J, Lussier Y, Dumayne C, Bichet DG, Lapointe JY. (2017)
MAP17 Is a Necessary Activator of Renal Na+/Glucose Cotransporter SGLT2.
J Am Soc Nephrol. 28(1):85-93. doi: 10.1681/ASN.2015111282

Martins C, Rueff J, Rodrigues AS. (2017)
Myristicin.
In “Handbook of Foodborn Diseases”. Food Microbiology series. Taylor and Francis CRC Press (in press)

Azevedo AP, Silva SN, Lima JP, Reichert A, Lima F, Júnior E, Rueff J. (2017)
DNA repair genes polymorphisms and genetic susceptibility to Philadelphia-negative myeloproliferative neoplasms in a Portuguese population: The role of base excision repair genes polymorphisms
Oncol Lett. 13(6):4641-4650. doi: 10.3892/ol.2017.6065

d’Oliveira Martins F, Gomes BC, Rodrigues AS, Rueff J. (2017)
Genetic Susceptibility in Acute Pancreatitis_Genotyping of GSTM1, GSTT1, GSTP1, CASP7, CASP8, CASP9, CASP10, LTA, TNFRSF1B, and TP53 Gene Variants.
Pancreas. 46(1):71-76. doi: 10.1097/MPA.0000000000000707

Gábelová A, El Yamani N, Alonso TI, Buliaková B, Srančíková A, Bábelová A, Pran ER, Fjellsbø LM, Elje E, Yazdani M, Silva MJ, Dušinská M. (2017)
Fibrous shape underlies the mutagenic and carcinogenic potential of nanosilver while surface chemistry affects the biosafety of iron oxide nanoparticles
Mutagenesis 32 (1): 193-202. doi: 10.1093/mutage/gew045

Graça D, Louro H, Santos J, Dias K, Almeida AJ, Gonçalves L, Silva MJ, Bettencourt A. (2017)
Toxicity screening of a novel poly(methylmethacrylate)-Eudragit nanocarrier on L929 fibroblasts.
Toxicol Lett. 276:129-137. doi: 10.1016/j.toxlet.2017.05.017

Caeiro S, Vaz-Fernandes P, Martinho A, Costa PM, Silva MJ, J. Lavinha J, Matias-Dias C, Machado A, Castanheira I, Costa MH. (2017)
Environmental risk assessment in a contaminated estuary: An integrated weight of evidence approach as a decision support tool.
Ocean & Coastal Management. 143:51-62

Collins AR, Annangi B, Rubio L, Marcos R, (…)Silva MJ, Leite PE, Ribeiro AR, Granjeiro JM, Grafström R, Prina-Mello A, Dusinska M. (2017)
High throughput toxicity screening and intracellular detection of nanomaterials.
Wiley Interdiscip Rev Nanomed Nanobiotechnol. 9(1):e1413. doi: 10.1002/wnan.1413

Feliciano A, Vaz F, Torres VM, Valentim-Coelho C, Silva R, Prosinecki V, Alexandre BM, Carvalho AS, Matthiesen R, Malhotra A, Pinto P, Bárbara C, Penque D. (2017)
Evening and morning peroxiredoxin-2 redox/oligomeric state changes in obstructive sleep apnea red blood cells: Correlation with polysomnographic and metabolic parameters.
Biochim Biophys Acta.1863(2):621-629. doi: 10.1016/j.bbadis.2016.11.019

Vicente Miranda H, Szego ÉM, Oliveira LM (…) Penque D, Engelender S, Zweckstetter M, Klucken J, Giorgini F, Quintas A, Outeiro TF. (2017)
Glycation potentiates α-synuclein-associated neurodegeneration in synucleinopathies.
Brain. April 10. doi: 10.1093/brain/awx056

Feliciano A, Vaz F, Valentim-Coelho C, Torres VM, Silva R, Prosinecki V, Alexandre BM, Almeida A, Almeida-Marques C, Carvalho AS, Matthiesen R, Malhotra A, Pinto P, Bárbara C, Penque D. (2017)
Evening and morning alterations in Obstructive Sleep Apnea red blood cell proteome.
Data Brief. 2017 Jan 16;11:103-110. doi: 10.1016/j.dib.2017.01.005.

de Oliveira RM, Vicente Miranda H (…)Penque D, Pais TF, Tong Q, Becker S, Kügler S, Lashuel HA, Steegborn C, Zweckstetter M, Outeiro TF. (2017)
The mechanism of sirtuin 2–mediated exacerbation of alpha-synuclein toxicity in models of Parkinson disease
PLoS Biol. 15(3):e2000374. doi: 10.1371/journal.pbio.2000374

Feliciano A, Linhas R, Marçôa R, Cysneiros A, Martinho C, Reis RP, Penque D, Pinto P, Bárbara C. (2017)
Hematological evaluation in males with obstructive sleep apnea before and after positive airway pressure.
Rev Port Pneumol. 23(2):71-78. doi: 10.1016/j.rppnen.2016.12.001.

Feliciano A, Oliveira MJ, Cysneiros A, Martinho C, Reis RP Penque D, Pinto P, Bárbara C. (2017)
Effects of positive airway pressure therapy on cardiovascular and metabolic markers in males with obstructive sleep apnea.
Rev Port Pneumol. 23(4):193-202. doi: 10.1016/j.rppnen.2017.02.010

2016

Gomes DP, Sequeira IJ, Figueiredo C, Rueff J, Brás A. (2016)
The Human Chromosomal Fragile Sites More Often Involved in Constitutional Deletions and Duplications – a Genetic and Statistical Assessment.
AIP Conference Proceedings 1790:080003. doi: 10.1063/1.4968684

Caroça C, Lima JP, Campelo P, Carolino E, Caria H, Paço J, Susana Silva SN. (2016)
Sickle Cell Trait, Malaria and Sensorineural Hearing Loss – A Case-Control Study from São Tomé and Príncipe.
Otolaryngol (Sunnyvale) 6:278. doi: 10.4172/2161-119X.1000278

Caroça C, de Matos TM, Ribeiro D, Lourenço V, Martins T, Campelo P, Fialho G, Silva SN, Paço J, Caria H. (2016)
Genetic Basis of Nonsyndromic Sensorineural Hearing loss in the Sub- Saharan African Island Population of São Tomé and Príncipe: The role of the DFNB1 locus?
OMICS 20(8):449-55. doi: 10.1089/omi.2016.0067

Brito Palma B, Fisher CW, Rueff J, Kranendonk M. (2016)
Prototype Systems Containing Human Cytochrome P450 for High-Throughput Real-Time Detection of DNA Damage by Compounds That Form DNA-Reactive Metabolites.
Chem Res Toxicol. 29(5):747-56. doi: 10.1021/acs.chemrestox.5b00455

Gomes BC, Santos B, Rueff J, Rodrigues AS. (2016)
Methods for Studying MicroRNA Expression and Their Targets in Formalin-Fixed, Paraffin-Embedded (FFPE) Breast Cancer Tissues.
Methods Mol Biol. 1395:189-205. doi: 10.1007/978-1-4939-3347-1_11

Gomes BC, Rueff J, Rodrigues AS. (2016)
MicroRNAs and Cancer Drug Resistance.
Methods Mol Biol. 1395:137-162. doi: 10.1007/978-1-4939-3347-1_9

Armada A, Martins C, Spengler G, Molnar J, Amaral L, Rodrigues AS, Viveiros M. (2016)
Fluorimetric Methods for Analysis of PERMEABILITY, Drug Transport Kinetics, and Inhibition of the ABCB1 Membrane Transporter.
Methods Mol Biol. 395:87-103. doi: 10.1007/978-1-4939-3347-1_7

Gromicho M, Rueff J, Rodrigues AS. (2016)
Dynamics of Expression of Drug Transporters: Methods for Appraisal.
Methods Mol Biol. 1395:75-85. doi: 10.1007/978-1-4939-3347-1_6

Rueff J, Rodrigues AS. (2016)
Cancer Drug Resistance: A Brief Overview from a Genetic Viewpoint.
Methods Mol Biol. 1395:1-18. doi: 10.1007/978-1-4939-3347-1_1

Gomes BC, Martins M, Lopes P, Morujão I, Oliveira M, Araújo A, Rueff J, Rodrigues AS. (2016)
Prognostic value of microRNA-203a expression in breast cancer.
Oncol Rep. 36(3):1748-56. doi: 10.3892/or.2016.4913

Lima JP, Silva SN, Rueff J, Pingarilho M. (2016)
Glycidamide genotoxicity modulated by Caspases genes polymorphisms.
Toxicol In Vitro. 34:123-127. doi: 10.1016/j.tiv.2016.03.018

Gonçalves J, Moreira E, Sequeira IJ, Rodrigues AS, Rueff J, Brás A. (2016)
Integration of HIV in the human genome – which sites are preferential? A genetic and statistical assessment.
Int J Genomics. 2016:2168590. doi: 10.1155/2016/2168590

Dias TM, Cardoso FA, Martins SAM, Martins VC, Cardoso S, Gaspar JF, Monteiro G, Freitas PP. (2016)
Implementing a strategy for on-chip detection of cell-free DNA fragments using GMR sensors: A translational application in cancer diagnostics using ALU elements.
Anal Methods. 8:119-128. doi: 10.1039/C5AY01587A

Louro H, Pinhão M, Santos J, Tavares A, Vital N, Silva MJ. (2016)
Evaluation of the cytotoxic and genotoxic effects of benchmark multi-walled carbon nanotubes in relation to their physicochemical properties.
Toxicol Lett. 262:123-134. doi: 10.1016/j.toxlet.2016.09.016

Assunção R, Silva MJ, Alvito P. (2016)
Challenges in risk assessment of multiple mycotoxins in food.
World Mycotoxin J. 9(5):791-811. doi: 10.3920/WMJ2016.2039

Costa JG, Saraiva N, Guerreiro PS, Louro H, Silva MJ, Miranda JP, Castro M, Batinic-Haberle I, Fernandes AS, Oliveira NG. (2016)
Ochratoxin A-induced cytotoxicity, genotoxicity and reactive oxygen species in kidney cells: An integrative approach of complementary endpoints.
Food Chem Toxicol. 87:65-76. doi: 10.1016/j.fct.2015.11.018

Dekkers S, Oomen AG, Bleeker EA, Vandebriel RJ, (…) Silva MJ, Prina-Mello A, Movia D, Nesslany F, Ribeiro AR, Leite PE, Groenewold M, Cassee FR, Sips AJ, Dijkzeul A, van Teunenbroek T, Wijnhoven SW. (2016)
Towards a nanospecific approach for risk assessment
Regul Toxicol Pharmacol. 80:46-59. doi: 10.1016/j.yrtph.2016.05.037

Torres VM1,2, Popovic L, Vaz F, Penque D. (2016)
Proteomics in the assessment of the therapeutic response of antineoplastic drugs: Strategies and practical applications
Methods Mol Biol. 1395:281-98. doi: 10.1007/978-1-4939-3347-1_16

2015

Costa S, Carvalho S, Costa C, Coelho P, Silva S, Santos LS, Gaspar JF, Porto B, Laffon B, Teixeira JP. (2015)
Increased levels of chromosomal aberrations and DNA damage in a group of workers exposed to formaldehyde.
Mutagenesis. 30(4):463-73. doi: 10.1093/mutage/gev002

Aires I, Fila M, Polidori D, Santos AR, Costa AB, Calado J. (2015)
Determination of the renal threshold for glucose excretion in Familial Renal Glucosuria.
Nephron. 2015;129(4):300-4. doi: 10.1159/000381677

Louro H, Bettencourt A, Gonçalves LM, Almeida AJ, Silva MJ. (2015)
Role of nanogenotoxicology studies in safety evaluation of nanomaterials.
In “Nanotechnology Applications for Tissue Engineering”. Eds S. Thomas S, Grohens Y, Ninan N. Elsevier Inc. Chapter 16, pp 263-88. doi: 10.1016/B978-0-323-32889-0.00016-9

Pinto MF, Louro H, Costa PM, Caeiro S, Silva MJ. (2015)
Exploring the potential interference of estuarine sediment contaminants with the DNA repair capacity of human hepatoma cells.
J Toxicol Environ Health A. 78(9):559-70. doi: 10.1080/15287394.2015.1006712

Tarantini A, Huet S, Jarry G, Lanceleur R, Poul M, Tavares A, Vital N, Louro H, Silva M, Fessard V. (2015)
Genotoxicity of synthetic amorphous silica nanoparticles in rats following short-term exposure. Part 1: oral route.
Environ Mol Mutagen. 56(2):218-27. doi: 10.1002/em.21935

Carvalho AS, Penque D, Matthiesen R. (2015)
Bottom up proteomics data analysis strategies to explore protein modifications and genomic variants.
Proteomics. 15(11):1789-92. doi: 10.1002/pmic.201400186

Feliciano A, Torres VM, Vaz F, Carvalho AS, Matthiesen R, Pinto P, Malhotra A, Bárbara C, Penque D. (2015)
Overview of proteomics studies in obstructive sleep apnea.
Sleep Med. 16(4):437-45. doi: 10.1016/j.sleep.2014.11.014

2014

Luís DV, Silva J, Tomaz AI, de Almeida RF, Larguinho M, Baptista PV, Martins LM, Silva TF, Borralho PM, Rodrigues CM, Rodrigues AS, Pombeiro AJ, Fernandes AR. (2014)
Insights into the mechanisms underlying the antiproliferative potential of a Co(II) coordination compound bearing 1,10-phenanthroline-5,6-dione: DNA and protein interaction studies.
J Biol Inorg Chem. 19(6):787-803. doi: 10.1007/s00775-014-1110-0

Martins M, Baptista PV, Mendo AS, Correia C, Videira P, Rodrigues AS, Muthukumaran J, Santos-Silva T, Silva A, da Silva MF, Gigante J, Duarte A, Gajewska M, Fernandes AR. (2014)
In vitro and in vivo biological characterization of the anti-proliferative potential of a cyclic trinuclear organotin(iv) complex.
Mol Biosyst. 12(3):1015-23. doi: 10.1039/c5mb00791g

Kranendonk M, Alves M,Antunes P, Rueff J. (2014)
Human Sulfotransferase 1A1-Dependent Mutagenicity of 12-Hydroxy-nevirapine: The Missing Link?
Chem Res Toxicol. 27:1967−1971. doi: 10.1021/tx5003113

Costa C, García-Lestón J, Costa S, Coelho P, Silva S, Pingarilho M, Valdiglesias V, Mattei F, Dall’Armi V, Bonassi S, Laffon B, Snawder J, Teixeira JP. (2014)
Is organic farming safer to farmers’ health? A comparison between organic and traditional farming.
Toxicol Lett. 230(2):166-76. doi: 10.1016/j.toxlet.2014.02.011

Esteves F, Lee CH, de Sousa B, Badura R, Seringa M, Fernandes C, Gaspar JF, Antunes F, Matos O. (2014)
(1-3)-beta-D-glucan in association with lactate dehydrogenase as biomarkers of Pneumocystis pneumonia (PcP) in HIV-infected patients.
Eur J Clin Microbiol Infect Dis. 33(7):1173-80. doi: 10.1007/s10096-014-2054-6

Giacomazzi J, Correia RL, Palmero EI, Gaspar JF, Almeida M, Portela C, Camey SA, Monteiro A, Pinheiro M, Peixoto A, Teixeira MR, Reis RM, Ashton-Prolla P. (2014)
The Brazilian founder mutation TP53 p.R337H is uncommon in Portuguese women diagnosed with breast cancer.
Breast J. 20(5):534-6. doi: 10.1111/tbj.12308

Silva J, Rodrigues AS, Videira PA, Lasri J, Charmier AJ, Pombeiro AJL, Fernandes AR. (2014)
Characterization of the antiproliferative potential and biological targets of a trans ketoimine platinum complex.
Inorg Chim Acta 423:156-167. doi: 10.1016/j.ica.2014.07.067

Costa EM, Silva S, Costa MR, Pereira M, Campos DA, Odila J, Madureira AR, Cardelle-Cobas A, Tavaria FK, Rodrigues AS, Pintado MM. (2014)
Chitosan mouthwash: Toxicity and in vivo validation.
Carbohydr Polym. 111:385-92. doi: 10.1016/j.carbpol.2014.04.046

Martins C, Doran C, Silva IC, Miranda C, Rueff J, Rodrigues AS. (2014)
Myristicin from nutmeg induces apoptosis via the mitochondrial pathway and down regulates genes of the DNA damage response pathways in human leukaemia K562 cells
Chem Biol Interact. 218:1-9. doi: 10.1016/j.cbi.2014.04.014

Pinto M, Costa PM, Louro H, Costa MH, Lavinha J, Caeiro S, Silva MJ. (2014)
Determining oxidative and non-oxidative genotoxic effects driven by estuarine sediment contaminants on a human hepatoma cell line
Sci Total Environ. 478:25-35. doi: 10.1016/j.scitotenv.2014.01.084

Tavares AM, Louro H, Antunes S, Quarré S, Simar S, De Temmerman PJ, Verleysen E, Mast J, Jensen KA, Norppa H, Nesslany F, Silva MJ. (2014)
Genotoxicity evaluation of nanosized titanium dioxide, synthetic amorphous silica and multi-walled carbon nanotubes in human lymphocytes
Toxicol In Vitro. 28(1):60-9. doi: 10.1016/j.tiv.2013.06.009

Dias E, Louro H, Pinto M, Santos T, Antunes S, Pereira P, Silva MJ. (2014)
Genotoxicity of microcystin-LR in in vitro and in vivo experimental models
Biomed Res Int. 2014:949521. doi: 10.1155/2014/949521

Pinto M, Costa PM, Louro H, Costa MH, Lavinha J, Caeiro S, Silva MJ. (2014)
Human hepatoma cells exposed to estuarine sediment contaminant extracts permitted the differentiation between cytotoxic and pro-mutagenic fractions
Environ Pollut. 185:141-8. doi: 10.1016/j.envpol.2013.10.034

Louro H, Tavares A, Vital N, Costa PM, Alverca E, Zwart E, de Jong WH, Fessard V, Lavinha J, Silva MJ. (2014)
Integrated approach to the in vivo genotoxic effects of a titanium dioxide nanomaterial using LacZ plasmid-based transgenic mice
Environ Mol Mutagen. 55(6):500-9. doi: 10.1002/em.21864

Pinto M, Rebola M, Louro H, Antunes AMM, S José S, Rocha M, Silva MJ, Cardoso AS. (2014)
Chlorinated Polycyclic Aromatic Hydrocarbons Associated with Drinking Water Disinfection: Synthesis, Formation under Aqueous Chlorination Conditions and Genotoxic Effects
Polycyclic Aromatic Compounds Vol. 34:356-371. doi:
10.1080/10406638.2014.891143

Costa PM, Pinto M, Vicente AM, Gonçalves C, Rodrigo AP, Louro H, Costa MH, Caeiro S, Silva MJ. (2014)
An integrative assessment to determine the genotoxic hazard of estuarine sediments: Combining cell and whole-organism responses
Front Genet. 5:437. doi: 10.3389/fgene.2014.00437.

Louro H, Pinto M, Vital N, Tavares AM, Costa PM, Silva MJ. (2014)
The LacZ plasmid based transgenic mouse model: an integrative approach to study the genotoxicity of nanomaterials.
In”Genotoxicity and DNA Repair: A Practical Approach”, L. María Sierra and Isabel Gaivão (eds.), Methods in Pharmacology and Toxicology, Springer-Humana Press, N Y, USA, pp. 451-478. doi: 10.1007/978-1-4939-1068-7_25

Carvalho AS, Ribeiro H, Voabil P, Penque D, Jensen ON, Molina H, Matthiesen R. (2014)
Global mass spectrometry and transcriptomics array based drug profiling provides novel insight into glucosamine induced endoplasmic reticulum stress
Mol Cell Proteomics. 13(12):3294-307. doi: 10.1074/mcp.M113.034363

2013

Aires I, Santos AR, Pratas J, Nolasco F, Calado J. (2013)
Hypouricaemia and hyperuricosuria in familial renal glucosuria.
Clin Kidney J. 6(5):523-5. doi: 10.1093/ckj/sft100

Bandarra S, Fernandes AS, Magro I, Guerreiro PS, Pingarilho M, Churchwell MI, Gil OM, Batinić-Haberle I, Gonçalves S, Rueff J, Miranda JP, Marques MM, Beland FA, Castro M, Gaspar JF, Oliveira NG. (2013)

http://www.ncbi.nlm.nih.gov/pubmed/?term=24150595

Mutagenesis. 28(6):721-9. doi: 10.1093/mutage/get052

Borges C, Mendonça D, Fernandes N, Pinheiro S, Vieira L, Mendonça A, Gaspar JF, Martins C, Diakanawma C, Rueff J, Braz J. (2013)
New Clerodanes from Tinnea antiscorbutica Welv.
Chem Soc. 24:1950-1956. doi: 10.5935/0103-5053.20130244

Coelho P, García-Lestón J, Costa S, Costa C, Silva S, Dall’Armi V, Zoffoli R, Bonassi St, Lima JP, Gaspar JF, Pásaro E, Laffon B, Teixeira JP. (2013)
Genotoxic effect of exposure to metal(loid)s. A molecular epidemiology survey of populations living and working in Panasqueira Mine area, Portugal.
Environ Int. 60:163-70. doi: 10.1016/j.envint.2013.08.014

Gromicho M, Magalhaes M, Torres F, Dinis J, Fernandes AR, Rendeiro P, Tavares P, Laires A, Rueff J, Rodrigues AS. (2013)
Instability of mRNA expression signatures of drug transporters in chronic myeloid leukemia patients resistant to imatinib.
Oncol Rep. 29:741-750. doi: 10.3892/or.2012.2153

Louro A, Peralta L, Soares S, Pereira A, Cunha G, Belchior A, Ferreira L, Monteiro Gil O, Louro H, Pinto P, Rodrigues AS, Silva MJ, Teles P. (2013)
Human exposure to indoor radon: a survey in the region of Guarda, Portugal.
Radiat Prot Dosimetry. 154(2):237-44. doi: 10.1093/rpd/ncs166

Palma BB, Silva e Sousa M, Urban P, Rueff J, Kranendonk M. (2013)
Functional characterization of eight human CYP1A2 variants: the role of cytochrome b5.
Pharmacogenet Genomics. 23(2):41-52. doi: 10.1097/FPC.0b013e32835c2ddf

Pingarilho M, Oliveira NG, Martins C, Gomes BC, Fernandes AS, Martins V, Labilloy A, Lima JP, Rueff J, Gaspar JF. (2013)
Induction of sister chromatid exchange by acrylamide and glycidamide in human lymphocytes: role of polymorphisms in detoxification and DNA-repair genes in the genotoxicity of glycidamide.
Mutat Res. 752(1-2):17. doi: 10.1016/j.mrgentox.2012.12.013

Ribeiro AL, Gaspar JF, Pereira T, Ribeiro V. (2013)
Lack of Relevance of HIF-1 alfa Polymorphisms in Breast Cancer in a Portuguese Population.
Anticancer Res. 33(6):2549-55.

Rodrigues AS, Gomes BC, Martins C, Gromicho M, Oliveira NG, Guerreiro PS, Rueff J. (2013)
DNA Repair and Resistance to Cancer Therapy.
In “New Research Directions in DNA Repair” (C. Chen Ed.). Intech Press. Pp. 489-528. doi: 10.5772/53952

Santos LS, Gomes BC, Gouveia R, Silva SN, Azevedo AP, Camacho V, Manita I, Gil OM, Ferreira TC, Limbert E, Rueff J, Gaspar JF. (2013)
The role of CCNH Val270Ala (rs2230641) and other nucleotide excision repair polymorphisms on individual susceptibility towards well-differentiated thyroid cancer.
Oncol Rep. 30(5):2458-66. doi: 10.3892/or.2013.2702

Sequeira IJ, Mexia JT, Santiago J, Mamede R, Silva E, Santos J, Faria D, Rueff J, Brás A. (2013)
Predominance of constitutional chromosomal rearrangements in human chromosomal fragile sites.
Open Journal of Genetics. 3:8-13. doi: 10.4236/ojgen.2013.32A3002

Rodrigues AS, Gomes BC, Martins C, Gromicho M, Oliveira NG, Guerreiro PS, Rueff J. (2013)
In “DNA Repair – New Research Directions”.
InTech Chapter 18; doi.org/10.5772/53952

https://www.intechopen.com/books/new-research-directions-in-dna-repair/dna-repair-and-resistance-to-cancer-therapy

Gromicho M, Magalhães M, Tores F, Dinis J, Fernandes, AR, Rendeiro P,Tavares, P, Laires, A, Rueff, J, Rodrigues, AS. (2013)
Instability of mRNA expression signatures of drug transporters in chronic myeloid leukemia patients resistant to imatinib
Oncology Rep 29(2):741-50. doi: 10.3892/or.2012.2153

Tavares A, Alvito P, Loureiro S, Louro H, Silva MJ. (2013)
Multi-mycotoxin determination in baby foods and in vitro combined cytotoxic effects of aflatoxin M and ochratoxin A
World Mycotoxin J. 6(4): 375-388. doi: 10.3920/WMJ2013.1554

Pacheco SA, Torres VM, Louro H, Gomes F, Lopes C, Marçal N, Fragoso E, Martins C, Oliveira CL, Hagenfeldt M, Bugalho-Almeida A, Penque D, Simões T. (2013)
Effects of occupational exposure to tobacco smoke: seeking for a link between environmental exposure and disease
J Toxicol Environ Health A. 76:311–327. doi: 10.1080/15287394.2013.757269

Louro H, Borges T, Silva MJ. (2013)
Nanomateriais manufaturados – Novos desafios para a saúde pública.
Revista Portuguesa de Saúde Pública, 31: 145-157. doi: 10.1016/j.rpsp.2012.12.004

Louro A, Peralta L, Soares S, Pereira A, Cunha G, Belchior A, Ferreira L, Monteiro Gil O, Louro H, Pinto P, Rodrigues AS, Silva MJ, Teles P. (2013)
Human exposure to indoor radon: a survey in the region of Guarda, Portugal.
Radiat Prot Dosimetry.154: 237-44.

O’Neil SE, Palviainen MJ, Ten Have S, Filiou M, Gonzalez A, Hodge K, Surinova S, Penque D, Baker MS. (2013)
Clinical proteomics stretch goals: EuPA 2012 roundtable report.
J Proteomics. 88:37-40. doi: 10.1016/j.jprot.2013.04.012

Pacheco SA, Torres VM, Louro H, Gomes F, Lopes C, Marçal N, Fragoso E, Martins C, Oliveira CL, Hagenfeldt M, Bugalho-Almeida A, Penque D, Simões T. (2013)
Effects of occupational exposure to tobacco smoke: is there a link between environmental exposure and disease?
J Toxicol Environ Health A. 76(4-5):311-27. doi: 10.1080/15287394.2013.757269

Vicente Miranda H, Xiang W, de Oliveira RM, Simões T, Pimentel J, Klucken J, Penque D, Outeiro TF. (2013)
Heat-mediated enrichment of α-synuclein from cells and tissue for assessing post-translational modifications.
J Neurochem. 126(5):673-84. doi: 10.1111/jnc.12251

Sebastiana M, Figueiredo A, Monteiro F, Martins J, Franco C, Coelho AV, Vaz F, Simões T, Penque D, Pais MS, Ferreira S. (2013)
A possible approach for gel-based proteomic studies in recalcitrant woody plants
Springerplus. ;2(1):210. doi: 10.1186/2193-1801-2-210

Smith LM, Kelleher NL ; Consortium for Top Down Proteomics: Linial M, Goodlett D, Langridge-Smith P, Goo YA, Safford G, Bonilla L, Kruppa G, Zubarev R, Rontree J, Chamot-Rooke J, Garavelli J, Heck A, Loo J, Penque D, Hornshaw M, Hendrickson C, Pasa-Tolic L, Borchers C, Chan D, Young N, Agar J, Masselon C, Gross M, McLafferty F, Tsybin Y, Ge Y, Sanders I, Langridge J, Whitelegge J, Marshall A. (2013)
Proteoform: a single term describing protein complexity.
Nat Methods. 10(3):186-7. doi: 10.1038/nmeth.2369

2012

Pingarilho M, Oliveira NG, Martins C, Fernandes AS, Lima JP, Rueff J, Gaspar JF. (2012)
Genomics and Cancer Drug Resistance.
Curr Pharm Biotechnol. 13(5):651-73. doi: 10.2174/138920112799857549

Pingarilho M, Oliveira NG, Martins C, Fernandes AS, Lima JP, Rueff J, Gaspar JF. (2012)
Genetic polymorphisms in detoxification and DNA repair genes and in vitro susceptibility to glycidamide-induced DNA damage.
Toxicol Environ Health A. 75(13-15):920-33. doi: 10.1080/15287394.2012.690709

Busto N, Valladolid J, Aliende C, Jalón FA, Manzano BR, Rodríguez AM, Gaspar JF, Martins C, Biver T, Espino G, Leal JM, García B. (2012)
Preparation of organometallic ruthenium-arene-diaminotriazine complexes as binding agents to DNA.
Chem Asian J. 7(4):788-801. doi: 10.1002/asia.201100883

García-Lestón J, Roma-Torres J, Vilares M, Pinto R, Prista J, Teixeira JP, Mayan O, Conde J, Pingarilho M, Gaspar JF, Pásaro E, Méndez J, Laffon B. (2012)
Genotoxic effects of occupational exposure to lead and influence of polymorphisms in genes involved in lead toxicokinetics and in DNA repair.
Environ Int. 43:29-36. doi: 10.1016/j.envint.2012.03.001

Esteves F, Gaspar J, de Sousa B, Antunes F, Mansinho K, Matos O. (2012)
Pneumocystis jirovecii multilocus genotyping in pooled DNA samples: a new approach for clinical and epidemiological studies.
Clin Microbiol Infect 18(6):E177-184. doi: 0.1111/j.1469-0691.2012.03828.x

Sakly A, Gaspar JF, Kerkeni E, Silva S, Teixeira JP, Chaari N, Ben Cheikh H. (2012)
Genotoxic damage in hospital workers exposed to ionizing radiation and metabolic gene polymorphisms.
J Toxicol Environ Health A. 75(13-15): 934-946. doi:10.1080/15287394.2012.690710.

Louro A, Peralta L, Soares S, Pereira A, Cunha G, Belchior A, Ferreira L, Gil OM, Louro H, Pinto P, Rodrigues AS, Silva MJ, Teles P. (2012)
Human Exposure to Indoor Radon: A Survey in the Region of Guarda, Portugal.
Radiat Prot Dosimetry 154:237-44. doi: 10.1093/rpd/ncs166

Sousa C, Fernandes F, Valentao P, Rodrigues AS, Coelho M, Teixeira JP, Silva S, Ferreres F, Pinho PG, Andrade PB. (2012)
Brassica oleracea L. Var. costata DC and Pieris brassicae L. Aqueous Extracts Reduce Methyl Methanesulfonate-Induced DNA Damage in V79 Hamster Lung Fibroblasts.
J Agric Food Chem 60:5380-5387. doi: 10.1021/jf300941s

Silva SN, Guerreiro D, Gomes M, Azevedo AP, Bezerra De Castro G, Rueff J, Gaspar JF. (2012)
SNPs/pools: a methodology for the identification of relevant SNPs in breast cancer epidemiology.
Oncol Rep 27(2):511-516. doi:10.3892/or.2011.1523

Sebastião NN,Fernandes N, Vieira L, Mendonça AJG, Gaspar JF, Martins C, Rueff J, Diakanamwa C, Mendonça, De IMD. (2012)
Three new labdanes isolated from Eragrostis viscose.
J Braz Chem Soc 23:1940-1950. doi: 10.1590/S0103-50532012005000067

Santos LS, Branco SC, Silva SN, Azevedo AP, Gil OM, Manita I, Ferreira TC, Limbert E, Rueff J, Gaspar JF. (2012)
Polymorphisms in base excision repair genes and thyroid cancer risk.
Oncol Rep 28:1859-68. doi:10.3892/or.2012.1975

Pingarilho M, Oliveira NG, Martins C, Fernandes AS, de Lima JP, Rueff J, Gaspar JF. (2012)
Genetic polymorphisms in detoxification and DNA repair genes and susceptibility to glycidamide-induced DNA damage.
J Toxicol Environ Health A 75:920-33 doi: 10.1080/15287394.2012.690709

Costa C, Costa S, Silva S, Coelho P, Botelho M, Gaspar J, Rueff J, Laffon B, Teixeira JP. (2012)
DNA damage and susceptibility assessment in industrial workers exposed to styrene.
J Toxicol Environ Health A 75: 735-46. doi: 10.1080/15287394.2012.688488

Fernandes AS, Costa J, Gaspar J, Rueff J, Cabral MF, Cipriano M, Castro M, Oliveira NG. (2012)
Development of pyridine-containing macrocyclic copper(II) complexes: potential role in the redox modulation of oxaliplatin toxicity in human breast cells.
Free Radic Res 46:1157-66. doi: 10.3109/10715762.2012.695869

Dinis J, Silva V, Gromicho M, Martins C, Laires A, Tavares P, Rendeiro P, Torres F, Rueff J, Rodrigues A. (2012)
DNA damage response in imatinib resistant chronic myeloid leukemia K562 cells.
Leuk Lymphoma 53:2004-14. doi: 10.3109/10428194.2012.681654

Martins C, Cação R, Cole KJ, Phillips DH, Laires A, Rueff J, Rodrigues AS. (2012)
Estragole: A weak direct-acting food-borne genotoxin and potential carcinogen
Mutagenesis. doi: 10.1016/j.mrgentox.2012.04.009

Rodrigues AS, Dinis J, Gromicho M, Martins C, Laires A, Rueff J. (2012)
Genomics and Cancer Drug Resistence.
Curr Pharm Biotechnol 13:651-673. doi: 10.2174/138920112799857549

Moutinho D, Marohnic CC, Panda SP, Rueff J, Masters BS, Kranendonk M. (2012)
Altered Human CYP3A4 Activity Caused by Antley-Bixler Syndrome-Related Variants od NADPH-Cytochrome P450 Oxidoreductase Measured in a Robust In Vitro System.
Drug Metab Dispos 40:754-760. doi: 10.1124/dmd.111.042820

Baptista PV. (2012)
RNA Quantification with Gold Nanoprobes for Cancer Diagnostics.
Clin Lab Med. 32(1):1-13.

Conde J, Ambrosone A, Sanz V, Hernandez Y, Marchesano V, Tian F, Child H, Berry CC, Ibarra MR, Baptista PV, Tortiglione C, de la Fuente JM. (2012)
Design of Multifunctional Gold Nanoparticles for In Vitro and In Vivo Gene Silencing.
ACS Nano. 2012; 6(9):8316-24.

Conde J, Baptista PV, Hernández Y, Sanz V, de la Fuente JM. (2012)
Modification of plasmid DNA topology by ‘histone-mimetic’ gold nanoparticles.
Nanomedicine (Lond). 2012; 7(11):1657-66.

Conde J, Doria G, Baptista P. (2012)
Noble Metal Nanoparticles Applications in Cancer.
Journal of Drug Delivery 2012; 2012:ID751075, 12 pages.

Conde J, Doria G, de la Fuente JM, Baptista PV. (2012)
RNA quantification using noble metal nanoprobes: simultaneous identification of several different mRNA targets using color multiplexing and application to cancer diagnostics.
Methods Mol Biol. 2012; 906:71-87.

Conde J, Rosa J, Lima JC, Baptista PV. (2012)
Nanophotonics for Molecular Diagnostics and Therapy Applications.
International Journal of Photoenergy 2012; 2012:ID 619530, 11 pages.

Costa CST, Costa S, Silva S, Coelho P, M. Botelho M, Gaspar JF, Rueff J, Laffon B, Teixeira JP. (2012)
DNA damage and susceptibility assessment in industrial workers exposed to styrene.
Toxicol Environ Health A. 2012;75(13-15):735-46.

Dinis J, Silva V, Gromicho M, Martins C, Laires A, Tavares P, Rendeiro P, Torres F, Rueff J, Rodrigues A. (2012)
DNA damage response in imatinib resistant chronic myeloid leukemia K562 cells.
Leuk Lymphoma. 2012; 53(10):2004-14.

Doria G, Conde J, Veigas B, Giestas L, Almeida C, Assunção M, Rosa J, Baptista PV. (2012)
Noble Metal Nanoparticles for Biosensing Applications.
Sensors 2012; 12(2), 1657-1687.

Esteves F, Gaspar JF, de Sousa B, Antunes F, Mansinho K, Matos O. (2012)
Pneumocystis jirovecii multilocus genotyping in pooled DNA samples: a new approach for clinical and epidemiological studies.
Clin Microbiol Infect. 2012; 18(6):E177-84.

Fernandes AS, Costa J, Gaspar JF, Rueff J, Cabral MF, Castro M, Oliveira NG. (2012)
Development of pyridine-containing macrocyclic copper(II) complexes: potential role in the redox modulation of oxaliplatin toxicity in human breast cells.
Free Radic Res. 2012; 46(9):1157-66.

García-Lestón J, Roma-Torres J, Vilares M, Pinto R, Prista J, Teixeira JP, Mayan O, Conde J, Pingarilho M, Gaspar JF, Pásaro E, Méndez J, Laffon B. (2012)
Genotoxic effects of occupational exposure to lead and influence of polymorphisms in genes involved in lead toxicokinetics and in DNA repair.
Environ Int. 2012; 43:29-36.

Gromicho M, Magalhaes M, Torres F, Dinis J, Fernandes AR, Rendeiro P, Tavares P, Laires A, Rueff J, Rodrigues AS. (2012)
Instability of mRNA expression signatures of drug transporters in chronic myeloid leukemia patients resistant to imatinib.
Oncol Rep. 2013; 29(2):741-50. Epub 2012 Nov 28.

Guirgis BSS, Sá e Cunha C, Gomes I, Cavadas M, Silva I, Doria G, Blatch GL, Baptista PV, Pereira E, Azzazy HME, Mota MM, Prudêncio M, Franco R. (2012)
Gold nanoparticle-based fluorescence immunoassay for Malaria antigen detection.
Anal Bioanal Chem. 2012; 402(3):1019-27.

Larguinho M, Baptista PV. (2012)
Gold and silver nanoparticles for clinical diagnostics — From genomics to proteomics.
J Proteomics. 2012; 75(10):2811-23.

Louro A, Peralta L, Soares S, Pereira A, Cunha G, Belchior A, Ferreira L, Gil OM, Louro H, Pinto P, Rodrigues AS, SIlva MJ, Teles P. (2012)
Human Exposure to Indoor Radon: A Survey in the Region of Guarda, Portugal.
Radiat Prot Dosimetry. 2013; 154(2):237-44. Epub 2012 Aug 16.

Machado D, I. Couto I, Perdigão J, Rodrigues L, Portugal I, Baptista P, Veigas B, Amaral L, Viveiros M. (2012)
Contribution of efflux to the emergence of isoniazid and multidrug resistance in Mycobacterium tuberculosis.
PLoS ONE. 2012; 7(4):e34538.

Pingarilho M, Oliveira NG, Martins C, AS. Fernandes, Lima JP, Rueff J, Gaspar JF. (2012)
Genetic polymorphisms in detoxification and DNA repair genes and in vitro susceptibility to glycidamide-induced DNA damage.
J Toxicol Environ Health A. 2012; 75(13-15):920-33.

Rodrigues AS, Dinis J, Gromicho M. Martins M, Laires A, Rueff J. (2012)
Genomics and Cancer Drug Resistance.
Curr Pharm Biotechnol. 2012; 13(5):651-73.

Rosa J, Conde J, De la Fuente JM, Lima JC, Baptista PV. (2012)
Gold-nanobeacons for real-time monitoring of RNA synthesis.
Biosens Bioelectron. 2012; 36(1):161-7.

Sakly A, Gaspar JF, Kerkeni E, Silva S, Teixeira JP, Chaari N, Cheikh HB. (2012)
Genotoxic damage in hospital workers exposed to ionizing radiation and metabolic gene polymorphisms.
J Toxicol Environ Health A. 2012; 75(13-15):934-46.

Santos MM, Queiroz MJ, Baptista PV. (2012)
Enhancement of antibiotic effect via gold: silver alloy nanoparticles.
Journal of Nanoparticle Research. 2012; 14:859-67.

Sanz V, Conde J, Hernández Y, Baptista PV, Ibarra MR, De la Fuente JM. (2012)
Effect of PEG biofunctional spacers and TAT peptide on dsRNA loading on gold nanoparticles.
Journal of Nanoparticle Research. 2012; 14:917-26.

Silva SN, D. Guerreiro D, Gomes M, A.P. Azevedo AP, De Castro GB, Rueff J, Gaspar JF. (2012)
SNPs/Pools: A methodology for the identification of relevant SNPs in breast cancer epidemiology.
Oncol Rep. 2012; 27(2):511-6.

Sousa C, Fernandes F, Valentão P, Rodrigues AS, Coelho M, Teixeira JP, Silva S, Ferreres F, de Pinho PG, Andrade PB. (2012)
Brassica oleracea L. Var. costata DC and Pieris brassicae L. Aqueous Extracts Reduce Methyl Methanesulfonate-Induced DNA Damage in V79 Hamster Lung Fibroblasts.
J Agric Food Chem. 2012; 60(21):5380-7.

Veigas B, Doria G, Baptista PV. (2012)
Nanodiagnostics for tuberculosis
In “Understanding Tuberculosis – Global Experiences and Innovative Approaches to the Diagnosis”. 2012; Pages 257-276, ISBN 979-953-307-078-9. Open Access Publishers.

Veigas B, Jacob J, Costa M, Santos D, Viveiros M, Inácio J, Martins R, Barquinha P, Fortunato E, Baptista PV. (2012)
Gold on Paper – Paper platform for Aunanoprobe TB detection.
Lab Chip. 2012; 12(22):4802-8.

Baptista PV, Doria G, Quaresma P, Cavadas M, Neves CS, Gomes I, Eaton P, Pereira E, Franco R. (2012)
Nanoparticles in Molecular Diagnostics
In “Progress in Molecular Biology and Translational Science”, 2011; Ed. A. Villaverde, Ed. P. Michael Conn, Elsevier Vol 104, Pages 427-488.