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	<title>ToxOmics &#187; admin</title>
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		<title>Publications</title>
		<link>http://cigmh.fcm.unl.pt/vestibulum-nibh-metus/publications/</link>
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		<description><![CDATA[<a href="http://www.ncbi.nlm.nih.gov/pubmed/?term=24150595" target="_blank">Mechanistic insights into glycidamide-induced cytotoxic and genotoxic effects in human mammary cells. </a>
Bandarra S, Fernandes AS, Magro I, Guerreiro PS, Pingarilho M, Churchwell MI, Gil OM, Batinić-Haberle I, Gonçalves S, Rueff J, Miranda JP, Marques MM, Beland FA, Castro M, Gaspar JF,Oliveira NG. Mutagenesis. 2013; 28(6):721-9.

<a href="http://www.ncbi.nlm.nih.gov/pubmed/?term=23660340" target="_blank">Bio-microfluidic platform for gold nanoprobe based DNA detection—application to Mycobacterium tuberculosis.</a>
Bernacka-Wojcik I, Lopes P, Vaz AC, Veigas B, Wojcik PJ, Simões P, Barata D, Fortunato E, Baptista PV, Águas H, Martins R. Biosens Bioelectron. 2013; 48:87-93.

]]></description>
				<content:encoded><![CDATA[<h3><span style="color: #008080;">2017</span></h3>
<p>Pandey A, Henderson CJ, Ishii Y, Kranendonk M, Backes W, Zanger U. (2017)<br />
<a href="https://doi.org/10.3389/fphar.2017.00881">Editorial: Role of Protein-Protein Interactions in Metabolism: Genetics, Structure, Function.</a><br />
Front. Pharmacol. 8:811. doi: 10.3389/fphar.2017.00881</p>
<p>Campelo D, Lautier T, Urban P, Esteves F, Bozonnet S, Truan G, Kranendonk M. (2017)<br />
<a href="https://doi.org/10.3389/fphar.2017.00755">The hinge segment of human NADPH-cytochrome P450 reductase in conformational switching: the critical role of ionic strength.<br />
</a>Front. Pharmacol. 8:755. doi: 10.3389/fphar.2017.00755</p>
<p>Azevedo AP, Silva SN, Reichert A, Lima F, Júnior E, Rueff J. (2017)<br />
<a href="https://www.spandidos-publications.com/br/7/4/370/abstract">Prevalence of the Janus kinase 2 V617F mutation in Philadelphia-negative myeloproliferative neoplasms in a Portuguese population. </a><br />
Biomedical Reports 7: 370-376. doi: 10.3892/br.2017.977</p>
<p>Caroça C, Vicente V, Campelo P, Chasqueira M, Caria H, Silva S, Paixão P, Paço J. (2017)<br />
<a href="https://www.ncbi.nlm.nih.gov/pubmed/28143602">Rubella in Sub-Saharan Africa and sensorineural hearing loss: a case control study.</a><br />
BMC Public Health. 17(1):146. doi: 10.1186/s12889-017-4077-2.</p>
<p>Caroça C, Vicente V, Campelo P, Chasqueira M, Caria H, Silva S, Paixão P, Paço J. (2017)<br />
<a href="https://www.ncbi.nlm.nih.gov/pubmed/?term=28599464">DNA repair genes polymorphisms and genetic susceptibility to Philadelphia-negative myeloproliferative neoplasms in a Portuguese population: The role of base excision repair genes polymorphisms.</a><br />
Oncol Lett. 13(6):4641-4650. doi: 10.3892/ol.2017.6065</p>
<p>Caroça C, Campelo P, Caria H, Paço J, Silva SN. (2017)<br />
<a href="https://scholar.google.com/scholar?hl=en&amp;q=G6PD+Variants%2C+Malaria+and+Sensorineural+Hearing+Loss+in+S%C3%A3o+Tom%C3%A9+andPr%C3%ADncipe%3A+A+Case-Control+Study.+&amp;btnG=Search">G6PD Variants, Malaria and Sensorineural Hearing Loss in São Tomé and Príncipe: A Case-Control Study.</a><br />
Int J Med Res Health Sci. 6(6): 8-16.</p>
<p>Coady MJ, El Tarazi A, Santer R, Bissonnette P, Sasseville LJ, Calado J, Lussier Y, Dumayne C, Bichet DG, Lapointe JY. (2017)<br />
<a href="https://www.ncbi.nlm.nih.gov/pubmed/?term=27288013">MAP17 Is a Necessary Activator of Renal Na+/Glucose Cotransporter SGLT2.</a><br />
J Am Soc Nephrol. 28(1):85-93. doi: 10.1681/ASN.2015111282</p>
<p>Martins C, Rueff J, Rodrigues AS. (2017)<br />
Myristicin.<br />
In &#8220;Handbook of Foodborn Diseases&#8221;. Food Microbiology series. Taylor and Francis CRC Press (in press)</p>
<p>Azevedo AP, Silva SN, Lima JP, Reichert A, Lima F, Júnior E, Rueff J. (2017)<br />
<a href="https://www.ncbi.nlm.nih.gov/pubmed/?term=28599464">DNA repair genes polymorphisms and genetic susceptibility to Philadelphia-negative myeloproliferative neoplasms in a Portuguese population: The role of base excision repair genes polymorphisms</a><br />
Oncol Lett. 13(6):4641-4650. doi: 10.3892/ol.2017.6065</p>
<p>d&#8217;Oliveira Martins F, Gomes BC, Rodrigues AS, Rueff J. (2017)<br />
<a href="https://www.ncbi.nlm.nih.gov/pubmed/?term=27984487">Genetic Susceptibility in Acute Pancreatitis_Genotyping of GSTM1, GSTT1, GSTP1, CASP7, CASP8, CASP9, CASP10, LTA, TNFRSF1B, and TP53 Gene Variants</a>.<br />
Pancreas. 46(1):71-76. doi: 10.1097/MPA.0000000000000707</p>
<p>Gábelová A, El Yamani N, Alonso TI, Buliaková B, Srančíková A, Bábelová A, Pran ER, Fjellsbø LM, Elje E, Yazdani M, Silva MJ, Dušinská M<br />
(2017)<br />
<a href="https://www.ncbi.nlm.nih.gov/pubmed/?term=27658822">Fibrous shape underlies the mutagenic and carcinogenic potential of nanosilver while surface chemistry affects the biosafety of iron oxide nanoparticles</a><br />
Mutagenesis 32 (1): 193-202. doi: 10.1093/mutage/gew045</p>
<p>Graça D, Louro H, Santos J, Dias K, Almeida AJ, Gonçalves L, Silva MJ, Bettencourt A. (2017)<br />
<a href="https://www.ncbi.nlm.nih.gov/pubmed/?term=28526447">Toxicity screening of a novel poly(methylmethacrylate)-Eudragit nanocarrier on L929 fibroblasts.</a><br />
Toxicol Lett. 276:129-137. doi: 10.1016/j.toxlet.2017.05.017</p>
<p>Caeiro S, Vaz-Fernandes P, Martinho A, Costa PM, Silva MJ, J. Lavinha J, Matias-Dias C, Machado A, Castanheira I, Costa MH. (2017)<br />
<a href="http://www.sciencedirect.com/science/article/pii/S0964569116302216">Environmental risk assessment in a contaminated estuary: An integrated weight of evidence approach as a decision support tool.</a><br />
Ocean &amp; Coastal Management. 143:51-62</p>
<p>Collins AR, Annangi B, Rubio L, Marcos R, (&#8230;)Silva MJ, Leite PE, Ribeiro AR, Granjeiro JM, Grafström R, Prina-Mello A, Dusinska M. (2017)<br />
<a href="https://www.ncbi.nlm.nih.gov/pubmed/?term=27273980">High throughput toxicity screening and intracellular detection of nanomaterials.</a><br />
Wiley Interdiscip Rev Nanomed Nanobiotechnol. 9(1):e1413. doi: 10.1002/wnan.1413</p>
<p>Feliciano A, Vaz F, Torres VM, Valentim-Coelho C, Silva R, Prosinecki V, Alexandre BM, Carvalho AS, Matthiesen R, Malhotra A, Pinto P, Bárbara C, Penque D. (2017)<br />
<a href="https://www.ncbi.nlm.nih.gov/pubmed/?term=27864139">Evening and morning peroxiredoxin-2 redox/oligomeric state changes in obstructive sleep apnea red blood cells: Correlation with polysomnographic and metabolic parameters.</a><br />
Biochim Biophys Acta.1863(2):621-629. doi: 10.1016/j.bbadis.2016.11.019</p>
<p>Vicente Miranda H, Szego ÉM, Oliveira LM (&#8230;) Penque D, Engelender S, Zweckstetter M, Klucken J, Giorgini F, Quintas A, Outeiro TF. (2017)<br />
<a href="https://www.ncbi.nlm.nih.gov/pubmed/?term=28398476">Glycation potentiates α-synuclein-associated neurodegeneration in synucleinopathies.</a><br />
Brain. April 10. doi: 10.1093/brain/awx056</p>
<p>Feliciano A, Vaz F, Valentim-Coelho C, Torres VM, Silva R, Prosinecki V, Alexandre BM, Almeida A, Almeida-Marques C, Carvalho AS, Matthiesen R, Malhotra A, Pinto P, Bárbara C, Penque D. (2017)<br />
<a href="https://www.ncbi.nlm.nih.gov/pubmed/?term=28149928">Evening and morning alterations in Obstructive Sleep Apnea red blood cell proteome.</a><br />
Data Brief. 2017 Jan 16;11:103-110. doi: 10.1016/j.dib.2017.01.005.</p>
<p>de Oliveira RM, Vicente Miranda H (&#8230;)Penque D, Pais TF, Tong Q, Becker S, Kügler S, Lashuel HA, Steegborn C, Zweckstetter M, Outeiro TF. (2017)<br />
<a href="https://www.ncbi.nlm.nih.gov/pubmed/?term=28257421">The mechanism of sirtuin 2–mediated exacerbation of alpha-synuclein toxicity in models of Parkinson disease</a><br />
PLoS Biol. 15(3):e2000374. doi: 10.1371/journal.pbio.2000374</p>
<p>Feliciano A, Linhas R, Marçôa R, Cysneiros A, Martinho C, Reis RP, Penque D, Pinto P, Bárbara C. (2017)<br />
<a href="https://www.ncbi.nlm.nih.gov/pubmed/?term=28153627">Hematological evaluation in males with obstructive sleep apnea before and after positive airway pressure.</a><br />
Rev Port Pneumol. 23(2):71-78. doi: 10.1016/j.rppnen.2016.12.001.</p>
<p>Feliciano A, Oliveira MJ, Cysneiros A, Martinho C, Reis RP Penque D, Pinto P, Bárbara C. (2017)<br />
<a href="https://www.ncbi.nlm.nih.gov/pubmed/28596012">Effects of positive airway pressure therapy on cardiovascular and metabolic markers in males with obstructive sleep apnea.</a><br />
Rev Port Pneumol. 23(4):193-202. doi: 10.1016/j.rppnen.2017.02.010</p>
<h3><span style="color: #008080;"><strong>2016</strong></span></h3>
<p>Gomes DP, Sequeira IJ, Figueiredo C, Rueff J, Brás A. (2016)<br />
<a href="http://aip.scitation.org/doi/abs/10.1063/1.4968684">The Human Chromosomal Fragile Sites More Often Involved in Constitutional Deletions and Duplications – a Genetic and Statistical Assessment.</a><br />
AIP Conference Proceedings 1790:080003. doi: 10.1063/1.4968684</p>
<p>Caroça C, Lima JP, Campelo P, Carolino E, Caria H, Paço J, Susana Silva SN. (2016)<br />
<a href="https://www.omicsonline.org/open-access/sickle-cell-trait-malaria-and-sensorineural-hearing-lossa-casecontrol-studyfrom-so-tom-and-prncipe-2161-119X-1000278.php?aid=82977&amp;view=mobile">Sickle Cell Trait, Malaria and Sensorineural Hearing Loss – A Case-Control Study from São Tomé and Príncipe.</a><br />
Otolaryngol (Sunnyvale) 6:278. doi: 10.4172/2161-119X.1000278</p>
<p>Caroça C, de Matos TM, Ribeiro D, Lourenço V, Martins T, Campelo P, Fialho G, Silva SN, Paço J, Caria H. (2016)<br />
<a href="https://www.ncbi.nlm.nih.gov/pubmed/?term=27501294">Genetic Basis of Nonsyndromic Sensorineural Hearing loss in the Sub- Saharan African Island Population of São Tomé and Príncipe: The role of the DFNB1 locus?</a><br />
OMICS 20(8):449-55. doi: 10.1089/omi.2016.0067</p>
<p>Palma BB, Moutinho D, Urban P, Rueff J, Kranendonk M. (2016)<br />
<a href="https://www.ncbi.nlm.nih.gov/pubmed/27476332">Cytochrome P450 expression system for high-throughput real-time detection of genotoxicity: Application to the study of human CYP1A2 variants.</a><br />
Mutat Res Genet Toxicol Environ Mutagen. 806:24-33. doi: 10.1016/j.mrgentox.2016.06.004</p>
<p>McCammon KM, Panda SP, Xia C, Kim JJ, Moutinho D, Kranendonk M, Auchus RJ, Lafer EM, Ghosh D, Martasek P, Kar R, Masters BS, Roman LJ. (2016)<br />
<a href="https://www.ncbi.nlm.nih.gov/pubmed/27496950">Instability of the Human Cytochrome P450 Reductase A287P Variant Is the Major Contributor to Its Antley-Bixler Syndrome-like Phenotype.</a><br />
J Biol Chem. 23;291(39):20487-502. doi: 10.1074/jbc.M116.716019</p>
<p>Brito Palma B, Fisher CW, Rueff J, Kranendonk M. (2016)<br />
<a href="https://www.ncbi.nlm.nih.gov/pubmed/27031942">Prototype Systems Containing Human Cytochrome P450 for High-Throughput Real-Time Detection of DNA Damage by Compounds That Form DNA-Reactive Metabolites.</a><br />
Chem Res Toxicol. 29(5):747-56. doi: 10.1021/acs.chemrestox.5b00455</p>
<p>Gomes BC, Santos B, Rueff J, Rodrigues AS. (2016)<br />
<a href="https://www.ncbi.nlm.nih.gov/pubmed/?term=26910075">Methods for Studying MicroRNA Expression and Their Targets in Formalin-Fixed, Paraffin-Embedded (FFPE) Breast Cancer Tissues.</a><br />
Methods Mol Biol. 1395:189-205. doi: 10.1007/978-1-4939-3347-1_11</p>
<p>Gomes BC, Rueff J, Rodrigues AS. (2016)<br />
<a href="https://www.ncbi.nlm.nih.gov/pubmed/?term=26910073">MicroRNAs and Cancer Drug Resistance.</a><br />
Methods Mol Biol. 1395:137-162. doi: 10.1007/978-1-4939-3347-1_9</p>
<p>Armada A, Martins C, Spengler G, Molnar J, Amaral L, Rodrigues AS, Viveiros M. (2016)<br />
<a href="https://www.ncbi.nlm.nih.gov/pubmed/?term=26910071">Fluorimetric Methods for Analysis of PERMEABILITY, Drug Transport Kinetics, and Inhibition of the ABCB1 Membrane Transporter.</a><br />
Methods Mol Biol. 395:87-103. doi: 10.1007/978-1-4939-3347-1_7</p>
<p>Gromicho M, Rueff J, Rodrigues AS. (2016)<br />
<a href="https://www.ncbi.nlm.nih.gov/pubmed/?term=26910070">Dynamics of Expression of Drug Transporters: Methods for Appraisal.</a><br />
Methods Mol Biol. 1395:75-85. doi: 10.1007/978-1-4939-3347-1_6</p>
<p>Rueff J, Rodrigues AS. (2016)<br />
<a href="https://www.ncbi.nlm.nih.gov/pubmed/?term=26910065">Cancer Drug Resistance: A Brief Overview from a Genetic Viewpoint.</a><br />
Methods Mol Biol. 1395:1-18. doi: 10.1007/978-1-4939-3347-1_1</p>
<p>Gomes BC, Martins M, Lopes P, Morujão I, Oliveira M, Araújo A, Rueff J, Rodrigues AS. (2016)<br />
<a href="https://www.ncbi.nlm.nih.gov/pubmed/?term=27431784">Prognostic value of microRNA-203a expression in breast cancer.</a><br />
Oncol Rep. 36(3):1748-56. doi: 10.3892/or.2016.4913</p>
<p>Lima JP, Silva SN, Rueff J, Pingarilho M. (2016)<br />
<a href="http://www.ncbi.nlm.nih.gov/pubmed/27062911">Glycidamide genotoxicity modulated by Caspases genes polymorphisms.</a><br />
Toxicol In Vitro. 34:123-127. doi: 10.1016/j.tiv.2016.03.018</p>
<p>Gonçalves J, Moreira E, Sequeira IJ, Rodrigues AS, Rueff J, Brás A. (2016)<br />
<a href="https://www.ncbi.nlm.nih.gov/pubmed/?term=27294106">Integration of HIV in the human genome – which sites are preferential? A genetic and statistical assessment</a>.<br />
Int J Genomics. 2016:2168590. doi: 10.1155/2016/2168590</p>
<p>Dias TM, Cardoso FA, Martins SAM, Martins VC, Cardoso S, Gaspar JF, Monteiro G, Freitas PP. (2016)<br />
<a href="http://pubs.rsc.org/en/Content/ArticleLanding/2016/AY/C5AY01587A#!divAbstract">Implementing a strategy for on-chip detection of cell-free DNA fragments using GMR sensors: A translational application in cancer diagnostics using ALU elements.</a><br />
Anal Methods. 8:119-128. doi: 10.1039/C5AY01587A</p>
<p>Louro H, Pinhão M, Santos J, Tavares A, Vital N, Silva MJ. (2016)<br />
<a href="https://www.ncbi.nlm.nih.gov/pubmed/?term=27702663">Evaluation of the cytotoxic and genotoxic effects of benchmark multi-walled carbon nanotubes in relation to their physicochemical properties.</a><br />
Toxicol Lett. 262:123-134. doi: 10.1016/j.toxlet.2016.09.016</p>
<p>Assunção R, Silva MJ, Alvito P. (2016)<br />
<a href="https://doi.org/10.3920/WMJ2016.2039">Challenges in risk assessment of multiple mycotoxins in food</a>.<br />
World Mycotoxin J. 9(5):791-811. doi: 10.3920/WMJ2016.2039</p>
<p>Costa JG, Saraiva N, Guerreiro PS, Louro H, Silva MJ, Miranda JP, Castro M, Batinic-Haberle I, Fernandes AS, Oliveira NG. (2016)<br />
<a href="https://www.ncbi.nlm.nih.gov/pubmed/26627377">Ochratoxin A-induced cytotoxicity, genotoxicity and reactive oxygen species in kidney cells: An integrative approach of complementary endpoints</a>.<br />
Food Chem Toxicol. 87:65-76. doi: 10.1016/j.fct.2015.11.018</p>
<p>Dekkers S, Oomen AG, Bleeker EA, Vandebriel RJ, (&#8230;) Silva MJ, Prina-Mello A, Movia D, Nesslany F, Ribeiro AR, Leite PE, Groenewold M, Cassee FR, Sips AJ, Dijkzeul A, van Teunenbroek T, Wijnhoven SW.<br />
(2016)<br />
Towards a nanospecific approach for risk assessment<br />
Regul Toxicol Pharmacol. 80:46-59. doi: 10.1016/j.yrtph.2016.05.037</p>
<p>https://www.ncbi.nlm.nih.gov/pubmed/?term=27255696</p>
<p>Torres VM1,2, Popovic L, Vaz F, Penque D.<br />
(2016)<br />
Proteomics in the assessment of the therapeutic response of antineoplastic drugs: Strategies and practical applications<br />
Methods Mol Biol. 1395:281-98. doi: 10.1007/978-1-4939-3347-1_16</p>
<p>https://www.ncbi.nlm.nih.gov/pubmed/?term=26910080</p>
<h3><span style="color: #008080;"><strong>2015</strong></span></h3>
<p>Costa S, Carvalho S, Costa C, Coelho P, Silva S, Santos LS, Gaspar JF, Porto B, Laffon B, Teixeira JP<br />
(2015)<br />
Increased levels of chromosomal aberrations and DNA damage in a group of workers exposed to formaldehyde.<br />
Mutagenesis. 30(4):463-73. doi: 10.1093/mutage/gev002</p>
<p>https://www.ncbi.nlm.nih.gov/pubmed/25711496</p>
<p>Aires I, Fila M, Polidori D, Santos AR, Costa AB, Calado J.<br />
(2015)<br />
Determination of the renal threshold for glucose excretion in Familial Renal Glucosuria.<br />
Nephron. 2015;129(4):300-4. doi: 10.1159/000381677</p>
<p>https://www.ncbi.nlm.nih.gov/pubmed/25896487</p>
<p>Louro H, Bettencourt A, Gonçalves LM, Almeida AJ, Silva MJ<br />
(2015)<br />
Role of nanogenotoxicology studies in safety evaluation of nanomaterials.<br />
In &#8220;Nanotechnology Applications for Tissue Engineering&#8221;. Eds S. Thomas S, Grohens Y, Ninan N. Elsevier Inc. Chapter 16, pp 263-88. doi: 10.1016/B978-0-323-32889-0.00016-9</p>
<p>http://www.sciencedirect.com/science/article/pii/B9780323328890000169</p>
<p>Pinto MF, Louro H, Costa PM, Caeiro S, Silva MJ<br />
(2015)<br />
Exploring the potential interference of estuarine sediment contaminants with the DNA repair capacity of human hepatoma cells.<br />
J Toxicol Environ Health A. 78(9):559-70. doi: 10.1080/15287394.2015.1006712</p>
<p>https://www.ncbi.nlm.nih.gov/pubmed/?term=25965191</p>
<p>Tarantini A, Huet S, Jarry G, Lanceleur R, Poul M, Tavares A, Vital N, Louro H, Silva M, Fessard V.<br />
(2015)<br />
Genotoxicity of synthetic amorphous silica nanoparticles in rats following short-term exposure. Part 1: oral route.<br />
Environ Mol Mutagen. 56(2):218-27. doi: 10.1002/em.21935</p>
<p>https://www.ncbi.nlm.nih.gov/pubmed/?term=25504566</p>
<p>Carvalho AS, Penque D, Matthiesen R.<br />
(2015)<br />
Bottom up proteomics data analysis strategies to explore protein modifications and genomic variants.<br />
Proteomics. 15(11):1789-92. doi: 10.1002/pmic.201400186</p>
<p>https://www.ncbi.nlm.nih.gov/pubmed/?term=25684358</p>
<p>Feliciano A, Torres VM, Vaz F, Carvalho AS, Matthiesen R, Pinto P, Malhotra A, Bárbara C, Penque D.<br />
(2015)<br />
Overview of proteomics studies in obstructive sleep apnea.<br />
Sleep Med. 16(4):437-45. doi: 10.1016/j.sleep.2014.11.014</p>
<p>https://www.ncbi.nlm.nih.gov/pubmed/?term=25770042</p>
<h3><span style="color: #008080;"><strong>2014</strong></span></h3>
<p>Luís DV, Silva J, Tomaz AI, de Almeida RF, Larguinho M, Baptista PV, Martins LM, Silva TF, Borralho PM, Rodrigues CM, Rodrigues AS, Pombeiro AJ, Fernandes AR.<br />
(2014)<br />
Insights into the mechanisms underlying the antiproliferative potential of a Co(II) coordination compound bearing 1,10-phenanthroline-5,6-dione: DNA and protein interaction studies.<br />
J Biol Inorg Chem. 19(6):787-803. doi: 10.1007/s00775-014-1110-0</p>
<p>https://www.ncbi.nlm.nih.gov/pubmed/?term=24481501</p>
<p>Martins M, Baptista PV, Mendo AS, Correia C, Videira P, Rodrigues AS, Muthukumaran J, Santos-Silva T, Silva A, da Silva MF, Gigante J, Duarte A, Gajewska M, Fernandes AR.<br />
(2014)<br />
In vitro and in vivo biological characterization of the anti-proliferative potential of a cyclic trinuclear organotin(iv) complex.<br />
Mol Biosyst. 12(3):1015-23. doi: 10.1039/c5mb00791g</p>
<p>https://www.ncbi.nlm.nih.gov/pubmed/?term=26842219</p>
<p>Kranendonk M, Alves M,Antunes P, Rueff J<br />
(2014)<br />
Human Sulfotransferase 1A1-Dependent Mutagenicity of 12-Hydroxy-nevirapine: The Missing Link?<br />
Chem Res Toxicol. 27:1967−1971. doi: 10.1021/tx5003113</p>
<p>http://www.ncbi.nlm.nih.gov/pubmed/25275777</p>
<p>Costa C, García-Lestón J, Costa S, Coelho P, Silva S, Pingarilho M, Valdiglesias V, Mattei F, Dall&#8217;Armi V, Bonassi S, Laffon B, Snawder J, Teixeira JP.<br />
(2014)<br />
Is organic farming safer to farmers&#8217; health? A comparison between organic and traditional farming.<br />
Toxicol Lett. 230(2):166-76. doi: 10.1016/j.toxlet.2014.02.011</p>
<p>http://www.ncbi.nlm.nih.gov/pubmed/24576785</p>
<p>Esteves F, Lee CH, de Sousa B, Badura R, Seringa M, Fernandes C, Gaspar JF, Antunes F, Matos O.<br />
(2014)<br />
(1-3)-beta-D-glucan in association with lactate dehydrogenase as biomarkers of Pneumocystis pneumonia (PcP) in HIV-infected patients.<br />
Eur J Clin Microbiol Infect Dis. 33(7):1173-80. doi: 10.1007/s10096-014-2054-6</p>
<p>http://www.ncbi.nlm.nih.gov/pubmed/24487911</p>
<p>Giacomazzi J, Correia RL, Palmero EI, Gaspar JF, Almeida M, Portela C, Camey SA, Monteiro A, Pinheiro M, Peixoto A, Teixeira MR, Reis RM, Ashton-Prolla P.<br />
(2014)<br />
The Brazilian founder mutation TP53 p.R337H is uncommon in Portuguese women diagnosed with breast cancer.<br />
Breast J. 20(5):534-6. doi: 10.1111/tbj.12308</p>
<p>https://www.ncbi.nlm.nih.gov/pubmed/?term=25052705</p>
<p>Silva J, Rodrigues AS, Videira PA, Lasri J, Charmier AJ, Pombeiro AJL, Fernandes AR.<br />
(2014)<br />
Characterization of the antiproliferative potential and biological targets of a trans ketoimine platinum complex.<br />
Inorg Chim Acta 423:156-167. doi: 10.1016/j.ica.2014.07.067</p>
<p>http://www.sciencedirect.com/science/article/pii/S0020169314004782?via%3Dihub</p>
<p>Costa EM, Silva S, Costa MR, Pereira M, Campos DA, Odila J, Madureira AR, Cardelle-Cobas A, Tavaria FK, Rodrigues AS, Pintado MM.<br />
(2014)<br />
Chitosan mouthwash: Toxicity and in vivo validation.<br />
Carbohydr Polym. 111:385-92. doi: 10.1016/j.carbpol.2014.04.046</p>
<p>https://www.ncbi.nlm.nih.gov/pubmed/?term=25037365</p>
<p>Martins C, Doran C, Silva IC, Miranda C, Rueff J, Rodrigues AS.<br />
(2014)<br />
Myristicin from nutmeg induces apoptosis via the mitochondrial pathway and down regulates genes of the DNA damage response pathways in human leukaemia K562 cells<br />
Chem Biol Interact. 218:1-9. doi: 10.1016/j.cbi.2014.04.014</p>
<p>http://www.ncbi.nlm.nih.gov/pubmed/24792648</p>
<p>Pinto M, Costa PM, Louro H, Costa MH, Lavinha J, Caeiro S, Silva MJ<br />
(2014)<br />
Determining oxidative and non-oxidative genotoxic effects driven by estuarine sediment contaminants on a human hepatoma cell line<br />
Sci Total Environ. 478:25-35. doi: 10.1016/j.scitotenv.2014.01.084</p>
<p>https://www.ncbi.nlm.nih.gov/pubmed/?term=24530582</p>
<p>Tavares AM, Louro H, Antunes S, Quarré S, Simar S, De Temmerman PJ, Verleysen E, Mast J, Jensen KA, Norppa H, Nesslany F, Silva MJ.<br />
(2014)<br />
Genotoxicity evaluation of nanosized titanium dioxide, synthetic amorphous silica and multi-walled carbon nanotubes in human lymphocytes<br />
Toxicol In Vitro. 28(1):60-9. doi: 10.1016/j.tiv.2013.06.009</p>
<p>https://www.ncbi.nlm.nih.gov/pubmed/?term=23811260</p>
<p>Dias E, Louro H, Pinto M, Santos T, Antunes S, Pereira P, Silva MJ.<br />
(2014)<br />
Genotoxicity of microcystin-LR in in vitro and in vivo experimental models<br />
Biomed Res Int. 2014:949521. doi: 10.1155/2014/949521</p>
<p>https://www.ncbi.nlm.nih.gov/pubmed/?term=24955368</p>
<p>Pinto M, Costa PM, Louro H, Costa MH, Lavinha J, Caeiro S, Silva MJ.<br />
(2014)<br />
Human hepatoma cells exposed to estuarine sediment contaminant extracts permitted the differentiation between cytotoxic and pro-mutagenic fractions<br />
Environ Pollut. 185:141-8. doi: 10.1016/j.envpol.2013.10.034</p>
<p>https://www.ncbi.nlm.nih.gov/pubmed/?term=24275312</p>
<p>Louro H, Tavares A, Vital N, Costa PM, Alverca E, Zwart E, de Jong WH, Fessard V, Lavinha J, Silva MJ.<br />
(2014)<br />
Integrated approach to the in vivo genotoxic effects of a titanium dioxide nanomaterial using LacZ plasmid-based transgenic mice<br />
Environ Mol Mutagen. 55(6):500-9. doi: 10.1002/em.21864</p>
<p>https://www.ncbi.nlm.nih.gov/pubmed/?term=24590610</p>
<p>Pinto M, Rebola M, Louro H, Antunes AMM, S José S, Rocha M, Silva MJ, Cardoso AS<br />
(2014)<br />
Chlorinated Polycyclic Aromatic Hydrocarbons Associated with Drinking Water Disinfection: Synthesis, Formation under Aqueous Chlorination Conditions and Genotoxic Effects<br />
Polycyclic Aromatic Compounds Vol. 34:356-371. doi:<br />
10.1080/10406638.2014.891143</p>
<p>http://www.tandfonline.com/doi/abs/10.1080/10406638.2014.891143#.VMuDSdKsU0M</p>
<p>Costa PM, Pinto M, Vicente AM, Gonçalves C, Rodrigo AP, Louro H, Costa MH, Caeiro S, Silva MJ.<br />
(2014)<br />
An integrative assessment to determine the genotoxic hazard of estuarine sediments: Combining cell and whole-organism responses<br />
Front Genet. 5:437. doi: 10.3389/fgene.2014.00437.</p>
<p>http://journal.frontiersin.org/article/10.3389/fgene.2014.00437/full</p>
<p>Louro H, Pinto M, Vital N, Tavares AM, Costa PM, Silva MJ<br />
(2014)<br />
The LacZ plasmid based transgenic mouse model: an integrative approach to study the genotoxicity of nanomaterials.<br />
In&#8221;Genotoxicity and DNA Repair: A Practical Approach&#8221;, L. María Sierra and Isabel Gaivão (eds.), Methods in Pharmacology and Toxicology, Springer-Humana Press, N Y, USA, pp. 451-478. doi: 10.1007/978-1-4939-1068-7_25</p>
<p>https://link.springer.com/protocol/10.1007%2F978-1-4939-1068-7_25</p>
<p>Carvalho AS, Ribeiro H, Voabil P, Penque D, Jensen ON, Molina H, Matthiesen R<br />
(2014)<br />
Global mass spectrometry and transcriptomics array based drug profiling provides novel insight into glucosamine induced endoplasmic reticulum stress<br />
Mol Cell Proteomics. 13(12):3294-307. doi: 10.1074/mcp.M113.034363</p>
<p>https://www.ncbi.nlm.nih.gov/pubmed/?term=25128556</p>
<p>&nbsp;</p>
<h3><strong>2013</strong></h3>
<p>Aires I, Santos AR, Pratas J, Nolasco F, Calado J.<br />
(2013)<br />
Hypouricaemia and hyperuricosuria in familial renal glucosuria.<br />
Clin Kidney J. 6(5):523-5. doi: 10.1093/ckj/sft100</p>
<p>https://www.ncbi.nlm.nih.gov/pubmed/26064518</p>
<p>Bandarra S, Fernandes AS, Magro I, Guerreiro PS, Pingarilho M, Churchwell MI, Gil OM, Batinić-Haberle I, Gonçalves S, Rueff J, Miranda JP, Marques MM, Beland FA, Castro M, Gaspar JF, Oliveira NG.<br />
(2013)<br />
Mechanistic insights into glycidamide-induced cytotoxic and genotoxic effects in human mammary cells.<br />
Mutagenesis. 28(6):721-9. doi: 10.1093/mutage/get052</p>
<p>http://www.ncbi.nlm.nih.gov/pubmed/?term=24150595</p>
<p>Borges C, Mendonça D, Fernandes N, Pinheiro S, Vieira L, Mendonça A, Gaspar JF, Martins C, Diakanawma C, Rueff J, Braz J<br />
(2013)<br />
New Clerodanes from Tinnea antiscorbutica Welv.<br />
Chem Soc. 24:1950-1956. doi: 10.5935/0103-5053.20130244</p>
<p>http://www.scielo.br/pdf/jbchs/v24n12/08.pdf</p>
<p>Coelho P, García-Lestón J, Costa S, Costa C, Silva S, Dall&#8217;Armi V, Zoffoli R, Bonassi St, Lima JP, Gaspar JF, Pásaro E, Laffon B, Teixeira JP.<br />
(2013)<br />
Genotoxic effect of exposure to metal(loid)s. A molecular epidemiology survey of populations living and working in Panasqueira Mine area, Portugal.<br />
Environ Int. 60:163-70. doi: 10.1016/j.envint.2013.08.014</p>
<p>http://www.ncbi.nlm.nih.gov/pubmed/?term=24036326</p>
<p>Gromicho M, Magalhaes M, Torres F, Dinis J, Fernandes AR, Rendeiro P, Tavares P, Laires A, Rueff J, Rodrigues AS.<br />
(2013)<br />
Instability of mRNA expression signatures of drug transporters in chronic myeloid leukemia patients resistant to imatinib.<br />
Oncol Rep. 29:741-750. doi: 10.3892/or.2012.2153</p>
<p>http://www.ncbi.nlm.nih.gov/pubmed/?term=23229016</p>
<p>Louro A, Peralta L, Soares S, Pereira A, Cunha G, Belchior A, Ferreira L, Monteiro Gil O, Louro H, Pinto P, Rodrigues AS, Silva MJ, Teles P.<br />
(2013)<br />
Human exposure to indoor radon: a survey in the region of Guarda, Portugal.<br />
Radiat Prot Dosimetry. 154(2):237-44. doi: 10.1093/rpd/ncs166</p>
<p>http://www.ncbi.nlm.nih.gov/pubmed/?term=22899215</p>
<p>Palma BB, Silva e Sousa M, Urban P, Rueff J, Kranendonk M.<br />
(2013)<br />
Functional characterization of eight human CYP1A2 variants: the role of cytochrome b5.<br />
Pharmacogenet Genomics. 23(2):41-52. doi: 10.1097/FPC.0b013e32835c2ddf</p>
<p>http://www.ncbi.nlm.nih.gov/pubmed/?term=23295917</p>
<p>Pingarilho M, Oliveira NG, Martins C, Gomes BC, Fernandes AS, Martins V, Labilloy A, Lima JP, Rueff J, Gaspar JF.<br />
(2013)<br />
Induction of sister chromatid exchange by acrylamide and glycidamide in human lymphocytes: role of polymorphisms in detoxification and DNA-repair genes in the genotoxicity of glycidamide.<br />
Mutat Res. 752(1-2):17. doi: 10.1016/j.mrgentox.2012.12.013</p>
<p>http://www.ncbi.nlm.nih.gov/pubmed/?term=23376767</p>
<p>Ribeiro AL, Gaspar JF, Pereira T, Ribeiro V.<br />
(2013)<br />
Lack of Relevance of HIF-1 alfa Polymorphisms in Breast Cancer in a Portuguese Population.<br />
Anticancer Res. 33(6):2549-55.</p>
<p>http://www.ncbi.nlm.nih.gov/pubmed/?term=23749907</p>
<p>Rodrigues AS, Gomes BC, Martins C, Gromicho M, Oliveira NG, Guerreiro PS, Rueff J.<br />
(2013)<br />
DNA Repair and Resistance to Cancer Therapy.<br />
In “New Research Directions in DNA Repair” (C. Chen Ed.). Intech Press. Pp. 489-528. doi: 10.5772/53952</p>
<p>http://www.intechopen.com/books/new-research-directions-in-dna-repair/dna-repair-and-resistance-to-cancer-therapy</p>
<p>Santos LS, Gomes BC, Gouveia R, Silva SN, Azevedo AP, Camacho V, Manita I, Gil OM, Ferreira TC, Limbert E, Rueff J, Gaspar JF.<br />
(2013)<br />
The role of CCNH Val270Ala (rs2230641) and other nucleotide excision repair polymorphisms on individual susceptibility towards well-differentiated thyroid cancer.<br />
Oncol Rep. 30(5):2458-66. doi: 10.3892/or.2013.2702</p>
<p>http://www.ncbi.nlm.nih.gov/pubmed/?term=23982724</p>
<p>Sequeira IJ, Mexia JT, Santiago J, Mamede R, Silva E, Santos J, Faria D, Rueff J, Brás A.<br />
(2013)<br />
Predominance of constitutional chromosomal rearrangements in human chromosomal fragile sites.<br />
Open Journal of Genetics. 3:8-13. doi: 10.4236/ojgen.2013.32A3002</p>
<p>http://www.scirp.org/journal/PaperInformation.aspx?paperID=35027#.UupWBbSUa0Y</p>
<p>Rodrigues AS, Gomes BC, Martins C, Gromicho M, Oliveira NG, Guerreiro PS, Rueff J.<br />
(2013)<br />
In “DNA Repair – New Research Directions”.<br />
InTech Chapter 18; doi.org/10.5772/53952</p>
<p>https://www.intechopen.com/books/new-research-directions-in-dna-repair/dna-repair-and-resistance-to-cancer-therapy</p>
<p>Gromicho M, Magalhães M, Tores F, Dinis J, Fernandes, AR, Rendeiro P,Tavares, P, Laires, A, Rueff, J, Rodrigues, AS.<br />
(2013)<br />
Instability of mRNA expression signatures of drug transporters in chronic myeloid leukemia patients resistant to imatinib<br />
Oncology Rep 29(2):741-50. doi: 10.3892/or.2012.2153</p>
<p>http://www.ncbi.nlm.nih.gov/pubmed/23229016</p>
<p>Tavares A, Alvito P, Loureiro S, Louro H, Silva MJ.<br />
(2013)<br />
Multi-mycotoxin determination in baby foods and in vitro combined cytotoxic effects of aflatoxin M and ochratoxin A<br />
World Mycotoxin J. 6(4): 375-388. doi: 10.3920/WMJ2013.1554</p>
<p>http://www.wageningenacademic.com/doi/10.3920/WMJ2013.1554</p>
<p>Pacheco SA, Torres VM, Louro H, Gomes F, Lopes C, Marçal N, Fragoso E, Martins C, Oliveira CL, Hagenfeldt M, Bugalho-Almeida A, Penque D, Simões T<br />
(2013)<br />
Effects of occupational exposure to tobacco smoke: seeking for a link between environmental exposure and disease<br />
J Toxicol Environ Health A. 76:311–327. doi: 10.1080/15287394.2013.757269</p>
<p>http://www.ncbi.nlm.nih.gov/pubmed/?term=23514073</p>
<p>Louro H, Borges T, Silva MJ (2013) .<br />
(2013)<br />
Nanomateriais manufaturados – Novos desafios para a saúde pública.<br />
Revista Portuguesa de Saúde Pública, 31: 145-157. doi: 10.1016/j.rpsp.2012.12.004</p>
<p>http://www.sciencedirect.com/science/article/pii/S0870902512000399</p>
<p>Louro A, Peralta L, Soares S, Pereira A, Cunha G, Belchior A, Ferreira L, Monteiro Gil O, Louro H, Pinto P, Rodrigues AS, Silva MJ, Teles P<br />
(2013)<br />
Human exposure to indoor radon: a survey in the region of Guarda, Portugal.<br />
Radiat Prot Dosimetry.154: 237-44.</p>
<p>O&#8217;Neil SE, Palviainen MJ, Ten Have S, Filiou M, Gonzalez A, Hodge K, Surinova S, Penque D, Baker MS.<br />
(2013)<br />
Clinical proteomics stretch goals: EuPA 2012 roundtable report.<br />
J Proteomics. 88:37-40. doi: 10.1016/j.jprot.2013.04.012</p>
<p>https://www.ncbi.nlm.nih.gov/pubmed/?term=23597926</p>
<p>Pacheco SA, Torres VM, Louro H, Gomes F, Lopes C, Marçal N, Fragoso E, Martins C, Oliveira CL, Hagenfeldt M, Bugalho-Almeida A, Penque D, Simões T.<br />
(2013)<br />
Effects of occupational exposure to tobacco smoke: is there a link between environmental exposure and disease?<br />
J Toxicol Environ Health A. 76(4-5):311-27. doi: 10.1080/15287394.2013.757269</p>
<p>https://www.ncbi.nlm.nih.gov/pubmed/?term=23514073</p>
<p>Vicente Miranda H, Xiang W, de Oliveira RM, Simões T, Pimentel J, Klucken J, Penque D, Outeiro TF.<br />
(2013)<br />
Heat-mediated enrichment of α-synuclein from cells and tissue for assessing post-translational modifications.<br />
J Neurochem. 126(5):673-84. doi: 10.1111/jnc.12251</p>
<p>https://www.ncbi.nlm.nih.gov/pubmed/?term=23534813</p>
<p>Sebastiana M, Figueiredo A, Monteiro F, Martins J, Franco C, Coelho AV, Vaz F, Simões T, Penque D, Pais MS, Ferreira S.<br />
(2013)<br />
A possible approach for gel-based proteomic studies in recalcitrant woody plants<br />
Springerplus. ;2(1):210. doi: 10.1186/2193-1801-2-210</p>
<p>https://www.ncbi.nlm.nih.gov/pubmed/?term=23724367</p>
<p>Smith LM, Kelleher NL ; Consortium for Top Down Proteomics: Linial M, Goodlett D, Langridge-Smith P, Goo YA, Safford G, Bonilla L, Kruppa G, Zubarev R, Rontree J, Chamot-Rooke J, Garavelli J, Heck A, Loo J, Penque D, Hornshaw M, Hendrickson C, Pasa-Tolic L, Borchers C, Chan D, Young N, Agar J, Masselon C, Gross M, McLafferty F, Tsybin Y, Ge Y, Sanders I, Langridge J, Whitelegge J, Marshall A.<br />
(2013)<br />
Proteoform: a single term describing protein complexity.<br />
Nat Methods. 10(3):186-7. doi: 10.1038/nmeth.2369</p>
<p>https://www.ncbi.nlm.nih.gov/pubmed/?term=23443629</p>
<h3><strong>2012</strong></h3>
<p>Pingarilho M, Oliveira NG, Martins C, Fernandes AS, Lima JP, Rueff J, Gaspar JF. B32<br />
(2012)<br />
Genomics and Cancer Drug Resistance.<br />
Curr Pharm Biotechnol. 13(5):651-73. doi: 10.2174/138920112799857549</p>
<p>http://www.ncbi.nlm.nih.gov/pubmed/22122479</p>
<p>Pingarilho M, Oliveira NG, Martins C, Fernandes AS, Lima JP, Rueff J, Gaspar JF.<br />
(2012)<br />
Genetic polymorphisms in detoxification and DNA repair genes and in vitro susceptibility to glycidamide-induced DNA damage.<br />
Toxicol Environ Health A. 75(13-15):920-33. doi: 10.1080/15287394.2012.690709</p>
<p>http://www.ncbi.nlm.nih.gov/pubmed/22788377</p>
<p>Busto N, Valladolid J, Aliende C, Jalón FA, Manzano BR, Rodríguez AM, Gaspar JF, Martins C, Biver T, Espino G, Leal JM, García B.<br />
(2012)<br />
Preparation of organometallic ruthenium-arene-diaminotriazine complexes as binding agents to DNA.<br />
Chem Asian J. 7(4):788-801. doi: 10.1002/asia.201100883</p>
<p>https://www.ncbi.nlm.nih.gov/pubmed/?term=22308008</p>
<p>García-Lestón J, Roma-Torres J, Vilares M, Pinto R, Prista J, Teixeira JP, Mayan O, Conde J, Pingarilho M, Gaspar JF, Pásaro E, Méndez J, Laffon B.<br />
(2012)<br />
Genotoxic effects of occupational exposure to lead and influence of polymorphisms in genes involved in lead toxicokinetics and in DNA repair.<br />
Environ Int. 43:29-36. doi: 10.1016/j.envint.2012.03.001</p>
<p>http://www.ncbi.nlm.nih.gov/pubmed/22466227</p>
<p>Esteves F, Gaspar J, de Sousa B, Antunes F, Mansinho K, Matos O.<br />
(2012)<br />
Pneumocystis jirovecii multilocus genotyping in pooled DNA samples: a new approach for clinical and epidemiological studies.<br />
Clin Microbiol Infect 18(6):E177-184. doi: 0.1111/j.1469-0691.2012.03828.x</p>
<p>http://www.ncbi.nlm.nih.gov/pubmed/22487139</p>
<p>Sakly A, Gaspar JF, Kerkeni E, Silva S, Teixeira JP, Chaari N, Ben Cheikh H.<br />
(2012)<br />
Genotoxic damage in hospital workers exposed to ionizing radiation and metabolic gene polymorphisms.<br />
J Toxicol Environ Health A. 75(13-15): 934-946. doi:10.1080/15287394.2012.690710.</p>
<p>http://www.ncbi.nlm.nih.gov/pubmed/22788378</p>
<p>Louro A, Peralta L, Soares S, Pereira A, Cunha G, Belchior A, Ferreira L, Gil OM, Louro H, Pinto P, Rodrigues AS, Silva MJ, Teles P.<br />
(2012)<br />
Human Exposure to Indoor Radon: A Survey in the Region of Guarda, Portugal.<br />
Radiat Prot Dosimetry 154:237-44. doi: 10.1093/rpd/ncs166</p>
<p>http://www.ncbi.nlm.nih.gov/pubmed/22899215</p>
<p>Sousa C, Fernandes F, Valentao P, Rodrigues AS, Coelho M, Teixeira JP, Silva S, Ferreres F, Pinho PG, Andrade PB.<br />
(2012)<br />
Brassica oleracea L. Var. costata DC and Pieris brassicae L. Aqueous Extracts Reduce Methyl Methanesulfonate-Induced DNA Damage in V79 Hamster Lung Fibroblasts.<br />
J Agric Food Chem 60:5380-5387. doi: 10.1021/jf300941s</p>
<p>http://www.ncbi.nlm.nih.gov/pubmed/22582708</p>
<p>Silva SN, Guerreiro D, Gomes M, Azevedo AP, Bezerra De Castro G, Rueff J, Gaspar JF.<br />
(2012)<br />
SNPs/pools: a methodology for the identification of relevant SNPs in breast cancer epidemiology.<br />
Oncol Rep 27(2):511-516. doi:10.3892/or.2011.1523</p>
<p>http://www.ncbi.nlm.nih.gov/pubmed/22024983</p>
<p>Sebastião NN,Fernandes N, Vieira L, Mendonça AJG, Gaspar JF, Martins C, Rueff J, Diakanamwa C, Mendonça, De IMD.<br />
(2012)<br />
Three new labdanes isolated from Eragrostis viscose.<br />
J Braz Chem Soc 23:1940-1950. doi: 10.1590/S0103-50532012005000067</p>
<p>http://www.scielo.br/scielo.php?script=sci_arttext&#038;pid=S0103-50532012001000025</p>
<p>Santos LS, Branco SC, Silva SN, Azevedo AP, Gil OM, Manita I, Ferreira TC, Limbert E, Rueff J, Gaspar JF.<br />
(2012)<br />
Polymorphisms in base excision repair genes and thyroid cancer risk.<br />
Oncol Rep 28:1859-68. doi:10.3892/or.2012.1975</p>
<p>http://www.ncbi.nlm.nih.gov/pubmed/22922830</p>
<p>Pingarilho M, Oliveira NG, Martins C, Fernandes AS, de Lima JP, Rueff J, Gaspar JF.<br />
(2012)<br />
Genetic polymorphisms in detoxification and DNA repair genes and susceptibility to glycidamide-induced DNA damage.<br />
J Toxicol Environ Health A 75:920-33 doi: 10.1080/15287394.2012.690709</p>
<p>http://www.ncbi.nlm.nih.gov/pubmed/22788377</p>
<p>Costa C, Costa S, Silva S, Coelho P, Botelho M, Gaspar J, Rueff J, Laffon B, Teixeira JP.<br />
(2012)<br />
DNA damage and susceptibility assessment in industrial workers exposed to styrene.<br />
J Toxicol Environ Health A 75: 735-46. doi: 10.1080/15287394.2012.688488</p>
<p>http://www.ncbi.nlm.nih.gov/pubmed/22788361</p>
<p>Fernandes AS, Costa J, Gaspar J, Rueff J, Cabral MF, Cipriano M, Castro M, Oliveira NG.<br />
(2012)<br />
Development of pyridine-containing macrocyclic copper(II) complexes: potential role in the redox modulation of oxaliplatin toxicity in human breast cells.<br />
Free Radic Res 46:1157-66. doi: 10.3109/10715762.2012.695869</p>
<p>http://www.ncbi.nlm.nih.gov/pubmed/22612279</p>
<p>Dinis J, Silva V, Gromicho M, Martins C, Laires A, Tavares P, Rendeiro P, Torres F, Rueff J, Rodrigues A.<br />
(2012)<br />
DNA damage response in imatinib resistant chronic myeloid leukemia K562 cells.<br />
Leuk Lymphoma 53:2004-14. doi: 10.3109/10428194.2012.681654</p>
<p>http://www.ncbi.nlm.nih.gov/pubmed/22475343</p>
<p>Martins C, Cação R, Cole KJ, Phillips DH, Laires A, Rueff J, Rodrigues AS.<br />
(2012)<br />
Estragole: A weak direct-acting food-borne genotoxin and potential carcinogen<br />
Mutagenesis. doi: 10.1016/j.mrgentox.2012.04.009</p>
<p>http://www.ncbi.nlm.nih.gov/pubmed/22561883</p>
<p>Rodrigues AS, Dinis J, Gromicho M, Martins C, Laires A, Rueff J.<br />
(2012)<br />
Genomics and Cancer Drug Resistence.<br />
Curr Pharm Biotechnol 13:651-673. doi: 10.2174/138920112799857549</p>
<p>http://www.ncbi.nlm.nih.gov/pubmed/22122479</p>
<p>Moutinho D, Marohnic CC, Panda SP, Rueff J, Masters BS, Kranendonk M.<br />
(2012)<br />
Altered Human CYP3A4 Activity Caused by Antley-Bixler Syndrome-Related Variants od NADPH-Cytochrome P450 Oxidoreductase Measured in a Robust In Vitro System.<br />
Drug Metab Dispos 40:754-760. doi: 10.1124/dmd.111.042820</p>
<p>http://www.ncbi.nlm.nih.gov/pubmed/22252407</p>
<p>Baptista PV.<br />
(2012)<br />
RNA Quantification with Gold Nanoprobes for Cancer Diagnostics.<br />
Clin Lab Med. 32(1):1-13.</p>
<p>http://www.sciencedirect.com/science/article/pii/S0272271211000989</p>
<p>Conde J, Ambrosone A, Sanz V, Hernandez Y, Marchesano V, Tian F, Child H, Berry CC, Ibarra MR, Baptista PV, Tortiglione C, de la Fuente JM.<br />
(2012)<br />
Design of Multifunctional Gold Nanoparticles for In Vitro and In Vivo Gene Silencing.<br />
ACS Nano. 2012; 6(9):8316-24.</p>
<p>http://www.ncbi.nlm.nih.gov/pubmed/22882598</p>
<p>Conde J, Baptista PV, Hernández Y, Sanz V, de la Fuente JM.<br />
(2012)<br />
Modification of plasmid DNA topology by &#8216;histone-mimetic&#8217; gold nanoparticles.<br />
Nanomedicine (Lond). 2012; 7(11):1657-66.</p>
<p>http://www.ncbi.nlm.nih.gov/pubmed/22583575</p>
<p>Conde J, Doria G, Baptista P.<br />
(2012)<br />
Noble Metal Nanoparticles Applications in Cancer.<br />
Journal of Drug Delivery 2012; 2012:ID751075, 12 pages.</p>
<p>http://www.hindawi.com/journals/jdd/2012/751075/</p>
<p>Conde J, Doria G, de la Fuente JM, Baptista PV.<br />
(2012)<br />
RNA quantification using noble metal nanoprobes: simultaneous identification of several different mRNA targets using color multiplexing and application to cancer diagnostics.<br />
Methods Mol Biol. 2012; 906:71-87.</p>
<p>http://www.ncbi.nlm.nih.gov/pubmed/22791425</p>
<p>Conde J, Rosa J, Lima JC, Baptista PV.<br />
(2012)<br />
Nanophotonics for Molecular Diagnostics and Therapy Applications.<br />
International Journal of Photoenergy 2012; 2012:ID 619530, 11 pages.</p>
<p>http://www.hindawi.com/journals/ijp/2012/619530/</p>
<p>Costa CST, Costa S, Silva S, Coelho P, M. Botelho M, Gaspar JF, Rueff J, Laffon B, Teixeira JP.<br />
(2012)<br />
DNA damage and susceptibility assessment in industrial workers exposed to styrene.<br />
Toxicol Environ Health A. 2012;75(13-15):735-46.</p>
<p>http://www.ncbi.nlm.nih.gov/pubmed/22788361</p>
<p>Dinis J, Silva V, Gromicho M, Martins C, Laires A, Tavares P, Rendeiro P, Torres F, Rueff J, Rodrigues A.<br />
(2012)<br />
DNA damage response in imatinib resistant chronic myeloid leukemia K562 cells,<br />
Leuk Lymphoma. 2012; 53(10):2004-14.</p>
<p>http://www.ncbi.nlm.nih.gov/pubmed/22475343</p>
<p>Doria G, Conde J, Veigas B, Giestas L, Almeida C, Assunção M, Rosa J, Baptista PV.<br />
(2012)<br />
Noble Metal Nanoparticles for Biosensing Applications.<br />
Sensors 2012; 12(2), 1657-1687.</p>
<p>http://www.mdpi.com/1424-8220/12/2/1657</p>
<p>Esteves F, Gaspar JF, de Sousa B, Antunes F, Mansinho K, Matos O.<br />
(2012)<br />
Pneumocystis jirovecii multilocus genotyping in pooled DNA samples: a new approach for clinical and epidemiological studies,<br />
Clin Microbiol Infect. 2012; 18(6):E177-84.</p>
<p>http://www.ncbi.nlm.nih.gov/pubmed/22487139</p>
<p>Fernandes AS, Costa J, Gaspar JF, Rueff J, Cabral MF, Castro M, Oliveira NG.<br />
(2012)<br />
Development of pyridine-containing macrocyclic copper(II) complexes: potential role in the redox modulation of oxaliplatin toxicity in human breast cells.<br />
Free Radic Res. 2012; 46(9):1157-66.</p>
<p>http://www.ncbi.nlm.nih.gov/pubmed/22612279</p>
<p>García-Lestón J, Roma-Torres J, Vilares M, Pinto R, Prista J, Teixeira JP, Mayan O, Conde J, Pingarilho M, Gaspar JF, Pásaro E, Méndez J, Laffon B.<br />
(2012)<br />
Genotoxic effects of occupational exposure to lead and influence of polymorphisms in genes involved in lead toxicokinetics and in DNA repair.<br />
Environ Int. 2012; 43:29-36.</p>
<p>http://www.ncbi.nlm.nih.gov/pubmed/22466227</p>
<p>Gromicho M, Magalhaes M, Torres F, Dinis J, Fernandes AR, Rendeiro P, Tavares P, Laires A, Rueff J, Rodrigues AS.<br />
(2012)<br />
Instability of mRNA expression signatures of drug transporters in chronic myeloid leukemia patients resistant to imatinib.<br />
Oncol Rep. 2013; 29(2):741-50. Epub 2012 Nov 28.</p>
<p>http://www.ncbi.nlm.nih.gov/pubmed/23229016</p>
<p>Guirgis BSS, Sá e Cunha C, Gomes I, Cavadas M, Silva I, Doria G, Blatch GL, Baptista PV, Pereira E, Azzazy HME, Mota MM, Prudêncio M, Franco R.<br />
(2012)<br />
Gold nanoparticle-based fluorescence immunoassay for Malaria antigen detection.<br />
Anal Bioanal Chem. 2012; 402(3):1019-27.</p>
<p>http://www.ncbi.nlm.nih.gov/pubmed/22089818</p>
<p>Larguinho M, Baptista PV.<br />
(2012)<br />
Gold and silver nanoparticles for clinical diagnostics — From genomics to proteomics.<br />
J Proteomics. 2012; 75(10):2811-23.</p>
<p>http://www.ncbi.nlm.nih.gov/pubmed/22119545</p>
<p>Louro A, Peralta L, Soares S, Pereira A, Cunha G, Belchior A, Ferreira L, Gil OM, Louro H, Pinto P, Rodrigues AS, SIlva MJ, Teles P.<br />
(2012)<br />
Human Exposure to Indoor Radon: A Survey in the Region of Guarda, Portugal.<br />
Radiat Prot Dosimetry. 2013; 154(2):237-44. Epub 2012 Aug 16.</p>
<p>http://www.ncbi.nlm.nih.gov/pubmed/22899215</p>
<p>Machado D, I. Couto I, Perdigão J, Rodrigues L, Portugal I, Baptista P, Veigas B, Amaral L, Viveiros M.<br />
(2012)<br />
Contribution of efflux to the emergence of isoniazid and multidrug resistance in Mycobacterium tuberculosis.<br />
PLoS ONE. 2012; 7(4):e34538.</p>
<p>http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0034538</p>
<p>Pingarilho M, Oliveira NG, Martins C, AS. Fernandes, Lima JP, Rueff J, Gaspar JF.<br />
(2012)<br />
Genetic polymorphisms in detoxification and DNA repair genes and in vitro susceptibility to glycidamide-induced DNA damage.<br />
J Toxicol Environ Health A. 2012; 75(13-15):920-33.</p>
<p>http://www.ncbi.nlm.nih.gov/pubmed/22788377</p>
<p>Rodrigues AS, Dinis J, Gromicho M. Martins M, Laires A, Rueff J.<br />
(2012)<br />
Genomics and Cancer Drug Resistance.<br />
Curr Pharm Biotechnol. 2012; 13(5):651-73.</p>
<p>http://www.ncbi.nlm.nih.gov/pubmed/22122479</p>
<p>Rosa J, Conde J, De la Fuente JM, Lima JC, Baptista PV.<br />
(2012)<br />
Gold-nanobeacons for real-time monitoring of RNA synthesis.<br />
Biosens Bioelectron. 2012; 36(1):161-7.</p>
<p>http://www.ncbi.nlm.nih.gov/pubmed/22541812</p>
<p>Sakly A, Gaspar JF, Kerkeni E, Silva S, Teixeira JP, Chaari N, Cheikh HB.<br />
(2012)<br />
Genotoxic damage in hospital workers exposed to ionizing radiation and metabolic gene polymorphisms.<br />
J Toxicol Environ Health A. 2012; 75(13-15):934-46.</p>
<p>http://www.ncbi.nlm.nih.gov/pubmed/22788378</p>
<p>Santos MM, Queiroz MJ, Baptista PV.<br />
(2012)<br />
Enhancement of antibiotic effect via gold: silver alloy nanoparticles.<br />
Journal of Nanoparticle Research. 2012; 14:859-67.</p>
<p>http://link.springer.com/article/10.1007%2Fs11051-012-0859-8</p>
<p>Sanz V, Conde J, Hernández Y, Baptista PV, Ibarra MR, De la Fuente JM.<br />
(2012)<br />
Effect of PEG biofunctional spacers and TAT peptide on dsRNA loading on gold nanoparticles.<br />
Journal of Nanoparticle Research. 2012; 14:917-26.</p>
<p>http://link.springer.com/article/10.1007/s11051-012-0917-2</p>
<p>Silva SN, D. Guerreiro D, Gomes M, A.P. Azevedo AP, De Castro GB, Rueff J, Gaspar JF.<br />
(2012)<br />
SNPs/Pools: A methodology for the identification of relevant SNPs in breast cancer epidemiology,<br />
Oncol Rep. 2012; 27(2):511-6.</p>
<p>http://www.ncbi.nlm.nih.gov/pubmed/22024983</p>
<p>Sousa C, Fernandes F, Valentão P, Rodrigues AS, Coelho M, Teixeira JP, Silva S, Ferreres F, de Pinho PG, Andrade PB.<br />
(2012)<br />
Brassica oleracea L. Var. costata DC and Pieris brassicae L. Aqueous Extracts Reduce Methyl Methanesulfonate-Induced DNA Damage in V79 Hamster Lung Fibroblasts,<br />
J Agric Food Chem. 2012; 60(21):5380-7.</p>
<p>http://www.ncbi.nlm.nih.gov/pubmed/22582708</p>
<p>Veigas B, Doria G, Baptista PV.<br />
(2012)<br />
Nanodiagnostics for tuberculosis<br />
In “Understanding Tuberculosis &#8211; Global Experiences and Innovative Approaches to the Diagnosis”. 2012; Pages 257-276, ISBN 979-953-307-078-9. Open Access Publishers.</p>
<p>http://www.intechopen.com/books/understanding-tuberculosis-global-experiences-and-innovative-approaches-to-the-diagnosis/nanodiagnostics-for-tuberculosis</p>
<p>Veigas B, Jacob J, Costa M, Santos D, Viveiros M, Inácio J, Martins R, Barquinha P, Fortunato E, Baptista PV.<br />
(2012)<br />
Gold on Paper – Paper platform for Aunanoprobe TB detection.<br />
Lab Chip. 2012; 12(22):4802-8.</p>
<p>http://www.ncbi.nlm.nih.gov/pubmed/23000923</p>
<p>Baptista PV, Doria G, Quaresma P, Cavadas M, Neves CS, Gomes I, Eaton P, Pereira E, Franco R.<br />
(2012)<br />
Nanoparticles in Molecular Diagnostics<br />
In “Progress in Molecular Biology and Translational Science”, 2011; Ed. A. Villaverde, Ed. P. Michael Conn, Elsevier Vol 104, Pages 427-488.</p>
<p>http://www.sciencedirect.com/science/bookseries/18771173/104/supp/C</p>
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